17OHP Coated Tube RIA Kit

17OHP Coated Tube RIA Kit

Configure Your Product:

SKU 0727110-CF
Price:
$0.00
In Stock
Request a quote
Description

Product Description

The 17OHP Coated Tube RIA Kit is intended for the measurement of 17a-hydroxyprogesterone in unextracted serum or plasma of adults and children. The steroid 17a-hydroxyprogesterone (17 OHP) is produced by both the adrenal cortex and gonads. Even though 17OHP has relatively little progestational activity, it is of intense clinical interest because it is the immediate precursor to 11-desoxycortisol (Cpd-S). Because Cpd-S is produced by 21-hydroxylation of 17OHP, measurement of 17OHP is a useful indirect indicator of 21-hydroxylase activity. In congenital 21-hydroxylase deficiency, the most common variety of congenital adrenal hyperplasia (CAH), 17OHP is secreted in abundant excess. It is moderately elevated in the 11-b-hydroxylase deficiency as well. Measurement of 17OHP is therefore valuable in the initial diagnosis of CAH.

Usage Statement

FDA cleared for In Vitro Diagnostic (IVD) use in the United States. CE Marked for IVD use outside the United States.

Key Applications

Endocrinology

Specifications
SKU 0727110-CF
Analyte / Target 17OHP (17 alpha hydroxyprogesterone)
Diagnostic Platforms RIA
Diagnostic Solutions Endocrinology
Disease Screened 17OHP
Evaluation Quantitative
Isotope 125I
Applications Endocrinology
Kit or Assay Type Solid Phase Radioimmunoassay
Product Families Description The 17OHP Coated Tube RIA Kit is intended for the measurement of 17a-hydroxyprogesterone in unextracted serum or plasma of adults and children. The steroid 17a-hydroxyprogesterone (17 OHP) is produced by both the adrenal cortex and gonads. Even though 17OHP has relatively little progestational activity, it is of intense clinical interest because it is the immediate precursor to 11-desoxycortisol (Cpd-S). Because Cpd-S is produced by 21-hydroxylation of 17OHP, measurement of 17OHP is a useful indirect indicator of 21-hydroxylase activity. In congenital 21-hydroxylase deficiency, the most common variety of congenital adrenal hyperplasia (CAH), 17OHP is secreted in abundant excess. It is moderately elevated in the 11-b-hydroxylase deficiency as well. Measurement of 17OHP is therefore valuable in the initial diagnosis of CAH.
Product Overview The kit is ready to use and includes the following components: Antibody Coated Tubes, 7 standards, and 125I-labeled tracer. Kits are manufactured once per month and have an 8 week shelf life.
Recommended Replacement For 07171102 | 07271105 | 07271305 | 07271302 | 07M5525303
Regulatory Compliance FDA Cleared (K854094/C)
Sample Type Serum|Plasma
Sample Volume 25 uL
Species Reactivity human
Standards 0, 0.10, 0.25, 1.0, 2.5, 10.0, 25.0 ng/mL
Storage and Handling Store at 2 - 8C
Trade Name ImmuChem
Usage Statement FDA cleared for In Vitro Diagnostic (IVD) use in the United States. CE Marked for IVD use outside the United States.