Dino

Tryptase (Purified Antigen)

Tryptase (Purified Antigen)

Packaging size: 10 µg

SKU 0857047
Price:
$267.85
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Description

Product Description

Tryptase is a glycoprotein released from mast cells during anaphylaxis, which performs a number of functions including catalyzing the activation of complement C3, converting prostromelysin to stromelysin (MMP-3), and cleaving fibrinogen resulting in a loss of clotting potential. Human tryptase is a major secretory protease of human lung mast cells.

Application Notes

Tryptase has been used in a study that purified and characterized recombinant rat mast cell protease 7 expressed in Pichia pastoris. Tryptase has also been used in a study to investigate drug allergies in mast cell disease.

Key Applications

Proteomics | Used in a study to investigate drug allergies in mast cell disease

Specifications
SKU 0857047
Application Notes Tryptase has been used in a study that purified and characterized recombinant rat mast cell protease 7 expressed in Pichia pastoris. Tryptase has also been used in a study to investigate drug allergies in mast cell disease.
Concentration 0.24 mg/ml
Formulation Details Liquid | 0.05M NaOAc; pH 5.0; containing 1.0M NaCl
Gene ID Human (7177)
Applications Proteomics | Used in a study to investigate drug allergies in mast cell disease
Pack Size 10 µg
Physical Appearance Liquid
Presentation Liquid. This product is in 0.05M NaOAc; pH 5.0; containing 1.0M NaCl. No Preservative.
Protein or Enzyme Type Other Proteins, Enzymes Peptides
Research Areas Inflammation
Source Human Lung
Specific Activity 59,700 mU/mg using n-benzoyl-Phe-Val-Arg-pNA as substrate.
Storage and Handling Store at -20°C. Avoid freeze/thaw cycles
Uniprot Number Q15661
Unit Definition One unit will hydrolyze one μM of N-benzoyl-Phe-Val-Arg-pNA per minute at 410 nm, pH 8.3, 25 °C. The assay uses 0.1M Tris buffer, pH 8.3. E,1%,280nm=30.3