Ethylenediamine Tetraacetic Acid

Ethylenediamine Tetraacetic Acid

Synonyms EDTA; (Ethylenedinitrilo)tetraacetic acid; Edathamil; Ethylenedinitrilotetraacetic acid

CAS Number: 10378-22-0 Molecular Formula: C10H16N2O8 Molecular Weight: 376.204 g/mol

Beilstein Registry Number: 1716295 EC Number: 200-449-4 MDL Number: MFCD00003541

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SKU 04800682-CF
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Description

Product Description

Ethylenediamine Tetraacetic Acid

Application Notes

Ethylenediamine tetraacetic acid (EDTA) is a calcium chelator used to eliminate inhibition of enzyme catalyzed reactions due to traces of heavy metals. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. EDTA prevents platelet aggregation and is therefore the preferred anticoagulant for platelet counts. It is an inhibitor of metalloproteases and metal-activated proteases. It acts as a chelator of the zinc ion in the active site of metalloproteases, but EDTA can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. EDTA interferes with biological processes which are metal-dependent. It is a buffer component.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Chelating agent||Buffer Component

Specifications
SKU 04800682-CF
Alternate Names EDTA; (Ethylenedinitrilo)tetraacetic acid; Edathamil; Ethylenedinitrilotetraacetic acid
Application Notes Ethylenediamine tetraacetic acid (EDTA) is a calcium chelator used to eliminate inhibition of enzyme catalyzed reactions due to traces of heavy metals. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. EDTA prevents platelet aggregation and is therefore the preferred anticoagulant for platelet counts. It is an inhibitor of metalloproteases and metal-activated proteases. It acts as a chelator of the zinc ion in the active site of metalloproteases, but EDTA can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. EDTA interferes with biological processes which are metal-dependent. It is a buffer component.
Beilstein Registry Number 1716295
EC Number 200-449-4
Format powder
Grade Electrophoresis Grade
Hazard Statements H319
Heavy Metals Heavy Metal (as Pb): <10 ppm, Iron (Fe): <50 ppm
Applications Chelating agent||Buffer Component
MDL # MFCD00003541
Melting Point 245 deg C
Molecular Formula C10H16N2O8
Molecular Weight 376.204 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Gloves
Physical Appearance White Powder
pKa 2.0, 2.7, 6.2, 10.3 (Lit.)
Product Families Description Ethylenediaminetetraacetic acid
Product Overview Ethylenediamine Tetraacetic Acid
Purity >99.5%
RTECS Number AH4025000
Safety Symbol GHS07
Solubility SOL IN SOLN OF ALKALI HYDROXIDES
Storage and Handling Store at Room Temperature(15-30 °C).
Sulphated Ash <0.1%
Typical Working Concentration EDTA is an inhibitor of metalloproteases and metal-activated proteases at an effective concentration of 1-10 µM.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Vapor Pressure 1.50X10-12 mm Hg at 25 deg C /Extrapolated/