Z-Val-Ala-Asp-(Ome)-Fluoromethylketone

Z-Val-Ala-Asp-(Ome)-Fluoromethylketone

Synonyms Z-Val-Ala-Asp-(OMe)-FMK; Z-VAD(OMe)-FMK

CAS Number: 187389-52-2 Molecular Formula: C22H30FN3O7 Molecular Weight: 467.494 g/mol

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SKU 03FK0090-CF
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$196.15
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Description

Product Description

Z-Val-Ala-Asp-(Ome)-Fluoromethylketone

Application Notes

Z-VAD(OMe)-FMK is an irreversible and cell permeable broad-spectrum Caspase Inhibitor. It has been shown to inhibit Fas-mediated apoptosis in Jurkat T cells and apoptosis in THP cells induced by diverse stimuli (including cycloheximide, thapsigargin, etoposide and staurosporine).

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

General Caspase Inhibitor||Apoptosis Inhibitor

Specifications
SKU 03FK0090-CF
Alternate Names Z-Val-Ala-Asp-(OMe)-FMK; Z-VAD(OMe)-FMK
Application Notes Z-VAD(OMe)-FMK is an irreversible and cell permeable broad-spectrum Caspase Inhibitor. It has been shown to inhibit Fas-mediated apoptosis in Jurkat T cells and apoptosis in THP cells induced by diverse stimuli (including cycloheximide, thapsigargin, etoposide and staurosporine).
Format solid
Applications General Caspase Inhibitor||Apoptosis Inhibitor
Molecular Formula C22H30FN3O7
Molecular Weight 467.494 g/mol
Physical Appearance White Solid
Product Families Description Z-Val-Ala-Asp-(OMe)-fluoromethylketone
Product Overview Z-Val-Ala-Asp-(Ome)-Fluoromethylketone
Protein or Enzyme Type Activators, Inhibitors & Substrates
Storage and Handling Keep cool and dry. Storage at room temperature does not effect this compound; however we recommend refrigerate at +4 °C. The solid product is stable in the desiccator at room temperature for 1 year. The stock solution is stable at -20 °C freezer for 6-8 months. Keep sealed after removing from the freezer until its temperature equilibrates with room temperature.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.