Ac-Asp-Glu-Val-Asp-7-Amino-4-Trifluoromethylcoumarin

Ac-Asp-Glu-Val-Asp-7-Amino-4-Trifluoromethylcoumarin

Synonyms Ac-Asp-Glu-Val-Asp-AFC; Ac-DEVD-AFC

CAS Number: 201608-14-2 Molecular Formula: C30H34F3N5O13 Molecular Weight: 729.619 g/mol

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SKU 03AFC138-CF
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Description

Product Description

Ac-Asp-Glu-Val-Asp-7-Amino-4-Trifluoromethylcoumarin

Application Notes

Ac-DEVD-AFC is a sensitive fluorescent substrate for the assay of caspase-3 activity. The trifluoromethyl substituent of the fluorophore improves the membrane permeability of the substrate.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Substrate for Assay of Casapse-3;7 and CPP-32

Specifications
SKU 03AFC138-CF
Application Notes Ac-DEVD-AFC is a sensitive fluorescent substrate for the assay of caspase-3 activity. The trifluoromethyl substituent of the fluorophore improves the membrane permeability of the substrate.
Format lyophilized powder
Applications Substrate for Assay of Casapse-3;7 and CPP-32
Molecular Formula C30H34F3N5O13
Molecular Weight 729.619 g/mol
Physical Appearance White lyophilized powder
Product Families Description Ac-Asp-Glu-Val-Asp-7-Amino-4-trifluoromethylcoumarin
Product Overview Ac-Asp-Glu-Val-Asp-7-Amino-4-Trifluoromethylcoumarin
Protein or Enzyme Type Activators, Inhibitors & Substrates
Storage and Handling Keep cool and dry. Desiccate AFC138 in solid form at room temperature. Store DMSO/DMF solutions at -20 °C. Material is stable for at least one year; if stored as recommended.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.