Dino

Ac-Lys-Pro-Arg-7-Amino-4-Trifluoromethylcoumarin

Ac-Lys-Pro-Arg-7-Amino-4-Trifluoromethylcoumarin

Synonyms Ac-Lys-Pro-Arg-AFC; Ac-KPR-AFC

CAS Number: Not yet assigned Molecular Formula: C29H39F3N8O6

Packaging size: 25 mg

SKU 03AFC13025
Price:
$599.90
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Description

Product Description

Ac-Lys-Pro-Arg-7-Amino-4-Trifluoromethylcoumarin

Application Notes

Ac-Lys-Pro-Arg-7-Amino-4-Trifluoromethylcoumarin is an fluorescent substrate for Tryptase detection. Tryptases are a group of trypsin-related serine proteases expressed in mast cells and basophils.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Substrate for Assay of Tryptase

Specifications
SKU 03AFC13025
Application Notes Ac-Lys-Pro-Arg-7-Amino-4-Trifluoromethylcoumarin is an fluorescent substrate for Tryptase detection. Tryptases are a group of trypsin-related serine proteases expressed in mast cells and basophils.
Format solid
Applications Substrate for Assay of Tryptase
Molecular Formula C29H39F3N8O6
Pack Size 25 mg
Physical Appearance White Solid
Product Families Description Ac-Lys-Pro-Arg-7-Amino-4-trifluoromethylcoumarin
Product Overview Ac-Lys-Pro-Arg-7-Amino-4-Trifluoromethylcoumarin
Protein or Enzyme Type Activators, Inhibitors & Substrates
Specificity Other trypsin-like enzymes are cleaved by tripeptide synthetic substrates. The absence of inhibition of Tryptase by classical inhibitors or serine esterase; including soybean trypsin inhibitor; clearly distinguishes tryptase from pancreatic trypsin and from most other serine esterases. Tryptase is inhibited by leupeptin; PMSF; and diisopropyl fluorophosphate.
Storage and Handling Keep cool and dry; Desiccate AFC- or AMC130 in solid form at room temperature. Store DMSO/DMF solutions at -20 °C. Material stable for at least one year; if stored as recommended.
Unit Definition One unit is the amount of enzyme that cleaves one micromole of AFC, AMC or MNA per minute, per milliliter at above described conditions.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.