Adenosine, U.S.P.

Adenosine, U.S.P.

Synonyms 9--D-Ribofuranosyladenine; Adenine riboside; Adenine-9--D-ribofuranoside;Adenocor;9-beta-D-Ribofuranosyl-9H-purin-6-amine;(3R,4R,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

CAS Number: 58-61-7 Molecular Formula: C10H13N5O4 Molecular Weight: 267.2

Beilstein Registry Number: 93029 EC Number: 200-389-9 MDL Number: MFCD00005752

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SKU 02199803-CF
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Description

Product Description

Adenosine is a purine nucleoside comprising a molecule of adenine attached to a ribose sugar molecule moiety via a β-N9-glycosidic bond. It plays an important role in energy transfer. It is an endogenous purine nucleoside that modulates physiological process wherein cellular signaling by adenosine occurs through four known adenosine receptor subtypes (A1, A2A, A2B, and A3) Adenosine is an anti-inflammatory agent at the A(2A) receptor. Cardioprotective effects may relate to activation of A1 adenosine receptors.

Application Notes

Adenosine is used in topical treatment of foot wounds in diabetes mellitus and also used for the treatment or prevention of cardiac arrhythmias (irregular heartbeat).It is used to cause dilation of the blood vessels.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Specifications
SKU 02199803-CF
Alternate Names 9--D-Ribofuranosyladenine; Adenine riboside; Adenine-9--D-ribofuranoside;Adenocor;9-beta-D-Ribofuranosyl-9H-purin-6-amine;(3R,4R,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Application Notes Adenosine is used in topical treatment of foot wounds in diabetes mellitus and also used for the treatment or prevention of cardiac arrhythmias (irregular heartbeat).It is used to cause dilation of the blood vessels.
Beilstein Registry Number 93029
Biochemical Physiological Actions Endogenous neurotransmitter at adenosine receptors. Cardioprotective effects may relate to activation of A1 adenosine receptors. The antiplatelet and anti−inflammatory actions of adenosine appear to be mediated via the A2 adenosine receptor. In contrast, adenosine appears to be a pro-inflammatory mediator in asthma and chronic obstructive pulmonary disease (COPD).
EC Number 200-389-9
Grade USP
Heavy Metals ≤0.001%
Loss on Drying ≤0.5%
MDL # MFCD00005752
Melting Point 233 - 238 °C
Molecular Formula C10H13N5O4
Molecular Weight 267.2
Optical Rotation -68.0° to -72.0° (c=2, NaOH 1:20)
Personal Protective Equipment Eyeshields, Gloves, respirator filter
Physical Appearance White powder
Residue on Ignition ≤0.1%
Storage and Handling -20 °C.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.