Dino

5-Fluorocytosine

5-Fluorocytosine

Synonyms 4-Amino-5-fluoro-2-hydroxypyrimidine; Flucystine; 4-amino-5-fluoro-2(1H)-pyrimidinone; Flucytosine

CAS Number: 2022-85-7 Molecular Formula: C4H4FN3O Molecular Weight: 129.094 g/mol

Beilstein Registry Number: 127285 EC Number: 217-968-7 MDL Number: MFCD00006035

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SKU 02199792-CF
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Description

Product Description

5-Fluorocytosine

Application Notes

5-Fluorocytosine is used in studies on TMP biosynthesis. It is used as an antifungal agent. It has also been used as a selection agent for plastids in transgenic plants.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Used in studies on TMP biosynthesis||Antifungal

Specifications
SKU 02199792-CF
Application Notes 5-Fluorocytosine is used in studies on TMP biosynthesis. It is used as an antifungal agent. It has also been used as a selection agent for plastids in transgenic plants.
Beilstein Registry Number 127285
Biochemical Physiological Actions 5-FC is deaminated by cytosine deaminase to product 5-fluorouracil, resulting in RNA miscoding. 5-Fluorocytosine inhibits DNA and RNA synthesis and interferes with ribosomal protein synthesis.
EC Number 217-968-7
Extinction Coefficient EmM= 8.91 (in 0.1 M HCl) (Lit.)
Format powder
Hazard Statements H361
Applications Used in studies on TMP biosynthesis||Antifungal
Loss on Drying ≤1.5%
Melting Point 296 °C
Molecular Formula C4H4FN3O
Molecular Weight 129.094 g/mol
Pack Size No
Personal Protective Equipment Eyeshields, Gloves, respirator filter
Physical Appearance White Powder
Product Families Description 5-Fluorocytosine
Product Overview 5-Fluorocytosine
Purity ≥98.5%
RTECS Number HA6040000
Safety Symbol GHS08
Solubility >19.4 [ug/mL]
Storage and Handling Store at -20 °C.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
UV Visible Absorbance λ max (0.1 N HCl) 284 - 286 nm