Xanthine Oxidase

Xanthine Oxidase

Synonyms Xanthine: oxygen oxidoreductase; XOD; EC 1.17.3.2

CAS Number: 9002-17-9

EC Number: 232-657-6 MDL Number: MFCD00082145

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SKU 02199518-CF
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Description

Product Description

Xanthine Oxidase

Application Notes

Xanthine oxidase can be used to generate superoxide radicals for use in the enzymatic assay of superoxide dismutase. The addition of xanthine oxidase as a superoxide donor to hepatic stellate cells (HSC) cell cultures strongly increased procollagen I synthesis.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Superoxide radical donor

Specifications
SKU 02199518-CF
Alternate Names Xanthine: oxygen oxidoreductase; XOD; EC 1.17.3.2
Application Notes Xanthine oxidase can be used to generate superoxide radicals for use in the enzymatic assay of superoxide dismutase. The addition of xanthine oxidase as a superoxide donor to hepatic stellate cells (HSC) cell cultures strongly increased procollagen I synthesis.
Biochemical Physiological Actions Xanthine oxidase is a molybdenum-containing enzyme that is found in the cytosol, and may be strongly inhibited by flavonoids. It plays a vital role in the metabolism of some drugs, as well as purines and pyrimidines. It is also known to be a biological source of reactive oxygen species.
EC Number 232-657-6
Extinction Coefficient E1% = 11.7(Lit.)
Format powder
Applications Superoxide radical donor
MDL # MFCD00082145
Personal Protective Equipment Eyeshields, Gloves, Respirator filter
Physical Appearance Light Yellow Powder
Product Families Description Xanthine Oxidase
Product Overview Xanthine Oxidase
RTECS Number RQ8455000
Source Buttermilk
Specific Activity Activity: 1 - 4 u/mg protein
Storage and Handling Store at -20 °C.
Unit Definition The amount of enzyme which catalyzes the oxidation of one micromole of xanthine to uric acid per minute at 25 °C and pH 7.5.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.