Leupeptin Trifluoroacetate Salt

Leupeptin Trifluoroacetate Salt

Synonyms Acetyl-Leu-Leu-Arg-al;Acetyl-Leu-Leu-Arg-al trifluoroacetate salt

CAS Number: 147385-61-3 Molecular Formula: C20H38N6O4·C2HF3O2 Molecular Weight: 540.585 g/mol

MDL Number: MFCD00133458

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SKU 02195623-CF
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Description

Product Description

Leupeptin Trifluoroacetate Salt

Application Notes

Leupeptin Trifluoroacetate Salt is used as inhibitor for trypsin, plasmin, papain, and cathepsin B.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Specifications
SKU 02195623-CF
Alternate Names Acetyl-Leu-Leu-Arg-al;Acetyl-Leu-Leu-Arg-al trifluoroacetate salt
Application Notes Leupeptin Trifluoroacetate Salt is used as inhibitor for trypsin, plasmin, papain, and cathepsin B.
Biochemical Physiological Actions Inhibitor of serine and cysteine proteases. Inhibits plasmin, trypsin, papain, calpain, and cathepsin B. Does not inhibit pepsin, cathepsins A and D, thrombin, or α-chymotrypsin. There have been numerous studies using leupeptin to protect against hearing loss caused by acoustic overstimulation or the ototoxic antibiotic gentamicin. (Loss of cochlear hair cells is believed to be mediated by calpain.)
Format powder
Hazard Statements H317
MDL # MFCD00133458
Molecular Formula C20H38N6O4·C2HF3O2
Molecular Weight 540.585 g/mol
Personal Protective Equipment Eyeshields, Gloves, respirator filter
Physical Appearance White Powder
Product Families Description Leupeptin
Product Overview Leupeptin Trifluoroacetate Salt
Purity ≥90%
Storage and Handling Store at-0 °C; desiccate; protect from light.
Typical Working Concentration 10-100 uM
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.