Dino

Pepstatin A

Pepstatin A

Synonyms Isovaleryl-L-valyl-L-valyl-[(3S, 4S)-4-amino-3-hydroxy-6- methylheptanoyl]-L- alanyl [3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid]; [1S-[1R*,2R*,4[R*[R*(R*)]]]]-N- (3-methyl-1-oxobutyl)-L-valyl-N-[4-[[2-[[1-(2-carboxy-1-hydroxyethyl)-3- methylbutyl] amino]-1-methyl-2-oxoethyl]amino]-2-hydroxy-1-(2-methylpropyl)-4-oxobutyl]-L-valinamide; N-isovaleryl-L-valyl-L-valyl-3-hydroxy-6-methyl-g-aminoheptanoyl-L- alanyl-3-hydroxy-6-methyl-g-aminoheptanoic acid

CAS Number: 26305-03-3 Molecular Formula: C34H63N5O9

Beilstein Registry Number: 2201362 EC Number: 247-600-0 MDL Number: MFCD00060740

Configure Your Product:

SKU 02195368-CF
Price:
$43.60
In Stock
Request a quote
Description

Product Description

Pepstatin A

Application Notes

Pepstatin A can be used in conjunction with E64-d and Leupeptin A to inhibit the degradation of autophagic cargo inside autophagosomes.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Inhibition||Protein Inhibitor

Specifications
SKU 02195368-CF
Application Notes Pepstatin A can be used in conjunction with E64-d and Leupeptin A to inhibit the degradation of autophagic cargo inside autophagosomes.
Beilstein Registry Number 2201362
Biochemical Physiological Actions Pepstatin A is an inhibitor of acid proteases (aspartyl peptidases). It forms a 1:1 complex with proteases such as pepsin, renin, cathepsin D, bovine chymosin, and protease B (Aspergillus niger). The inhibitor is highly selective and does not inhibit thiol proteases, neutral proteases, or serine proteases. Solubilized γ-secretase and retroviral protease are also inhibited by Pepstatin A. It has been used to characterize proteases from several sources.
EC Number 247-600-0
Hazard Statements H317
Applications Inhibition||Protein Inhibitor
Molecular Formula C34H63N5O9
Personal Protective Equipment Eyeshields, Gloves,respirator filter
Physical Appearance White Powder
Product Families Description Pepstatin A
Product Overview Pepstatin A
RTECS Number SC6155000
Storage and Handling Store at -0 °C; protect from light.
Typical Working Concentration Effective concentration is approximately 1 uM (0.5 to 1.0 ug/mL).
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.