Ethylene Glycol-Bis-(Β-Amino-Ethylether)-N,N,N′,N′-Tetraacetic Acid

Ethylene Glycol-Bis-(Β-Amino-Ethylether)-N,N,N′,N′-Tetraacetic Acid

Synonyms EGTA; GEDTA; O,O'-bis(2-aminoethyl) ethyleneglycol-N,N,N',N'-tetraacetic acid; Ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetracetic acid; Egtazic acid; Ethylene-bis(oxyethylenenitrilo)tetraacetic acid; Glycol ether diamine tetraacetic acid

CAS Number: 67-42-5 Molecular Formula: C14H24N2O10 Molecular Weight: 380.35 g/mol

Beilstein Registry Number: 1717370 EC Number: 200-651-2 MDL Number: MFCD00004291

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SKU 02195174-CF
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Description

Product Description

Ethylene Glycol-Bis-(Β-Amino-Ethylether)-N,N,N′,N′-Tetraacetic Acid

Application Notes

Ethylene Glycol-bis-(beta-aminoethylether)-N,N,N',N'-tetraacetic Acid is a chelating agent for determination of calcium in the presence of magnesium; it can also detect cadmium in the presence of zinc. It is also useful for the removal of heavy metal ions in biological systems. It is shown to activate Ca2+- stimulated ATPase in rat liver plasma membranes and induce apoptosis in PC12 cells. It also inhibits the zinc-dependent endopeptidases, matrix metalloproteinases.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Chelating agent

Specifications
SKU 02195174-CF
Alternate Names EGTA; GEDTA; O,O'-bis(2-aminoethyl) ethyleneglycol-N,N,N',N'-tetraacetic acid; Ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetracetic acid; Egtazic acid; Ethylene-bis(oxyethylenenitrilo)tetraacetic acid; Glycol ether diamine tetraacetic acid
Application Notes Ethylene Glycol-bis-(beta-aminoethylether)-N,N,N',N'-tetraacetic Acid is a chelating agent for determination of calcium in the presence of magnesium; it can also detect cadmium in the presence of zinc. It is also useful for the removal of heavy metal ions in biological systems. It is shown to activate Ca2+- stimulated ATPase in rat liver plasma membranes and induce apoptosis in PC12 cells. It also inhibits the zinc-dependent endopeptidases, matrix metalloproteinases.
Beilstein Registry Number 1717370
EC Number 200-651-2
Format Crystalline
Applications Chelating agent
MDL # MFCD00004291
Molecular Formula C14H24N2O10
Molecular Weight 380.35 g/mol
Personal Protective Equipment Eyeshields, Gloves, Respirator filter
Physical Appearance White Crystalline Powder
pKa < 2, 2.7, 8.8, and 9.5 (Lit.)
Product Families Description Ethylene glycol-bis(β-aminoethylether-N,N,N',N'-tetraacetic acid
Product Overview Ethylene Glycol-Bis-(Β-Amino-Ethylether)-N,N,N′,N′-Tetraacetic Acid
Purity ≥98%
RTECS Number AH3760000
Storage and Handling Store at Room Temperature (15-30 °C).
Typical Working Concentration as a metalloprotease inhibitor (effective concentration is typically 1 to 10 µM)
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.