α-Thrombin

α-Thrombin

Synonyms Factor IIa; Thrombin from bovine plasma

CAS Number: 2594047

MDL Number: MFCD00166053

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SKU 02194921-CF
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Description

Product Description

Α-Thrombin

Application Notes

Thrombin is used for site specific cleavage of recombinant fusion proteins containing an accessible thrombin recognition site for removal of affinity tags. Thrombin has been used in a study to assess persistent hypocoagulability in patients with septic shock.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Specifications
SKU 02194921-CF
Application Notes Thrombin is used for site specific cleavage of recombinant fusion proteins containing an accessible thrombin recognition site for removal of affinity tags. Thrombin has been used in a study to assess persistent hypocoagulability in patients with septic shock.
Biochemical Physiological Actions Serine protease that selectively cleaves Arg-Gly bonds in fibrinogen to form fibrin and fibrinopeptides A and B.
Extinction Coefficient E (1%/1 cm, 280nm): 19.5 (Lit.)
Format solution
Formulation Details Supplied in 50% Glycerol/H2O (vol/vol)
Gene ID cow ... F2(280685)
Hazard Statements H317-H315-H319-H334-H335
Personal Protective Equipment Respiratory protection: Breathing apparatus only if aerosol or dust is formed. Hand protection: Handle with gloves Skin and body protection: Usual safety precautions while handling the product will provide adequate protection against this potential effect. Eye protection: Safety glasses with side-shields Hygiene measures: Handle in accordance with good industrial hygiene and safety practice.
Physical Appearance Clear; Colorless Solution
Product Families Description Thrombin
Product Overview Α-Thrombin
Safety Symbol GHS07, GHS08
Source Bovine
Storage and Handling Store at -20 °C.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.