Staurosporine

Staurosporine

Synonyms Antibiotic AM-2282

CAS Number: 62996-74-1 Molecular Formula: C28H26N4O3 Molecular Weight: 466.541 g/mol

Beilstein Registry Number: 1060573 MDL Number: MFCD00077402

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SKU 02194805-CF
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Description

Product Description

Staurosporine

Application Notes

Staurosporine from Streptomyces sp. was used to induce cell death in MDCK, 293T, Vero, HeLa, and Swiss Webster primary macrophage cells. It was used to study the effect of caspase activation on human sperm quality.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Specifications
SKU 02194805-CF
Application Notes Staurosporine from Streptomyces sp. was used to induce cell death in MDCK, 293T, Vero, HeLa, and Swiss Webster primary macrophage cells. It was used to study the effect of caspase activation on human sperm quality.
Beilstein Registry Number 1060573
Biochemical Physiological Actions Potent inhibitor of phospholipid/calcium-dependent protein kinase. Inhibits the upregulation of VEGF expression in tumor cells.Partially reverses MDR, sensitizing cells with MDR phenotype to cytotoxic agents. Inhibits Pgp phosphorylation. However, functional significance of Pgp phosphorylation is ill defined.
Format film
Grade Molecular biology reagent
Hazard Statements H340-H350
Molecular Formula C28H26N4O3
Molecular Weight 466.541 g/mol
Personal Protective Equipment Eyeshields, full-face particle respirator , Gloves, respirator cartridge, respirator filter
Physical Appearance White film around the bottom of the vial
Product Families Description Staurosporine
Product Overview Staurosporine
Purity ≥98%
Safety Symbol GHS08
Source Streptomyces sp.
Storage and Handling +4°C; protect from light
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.