Choline Chloride

Choline Chloride

Synonyms Choline Hydrochloride; Hepacholine; (2-Hydroxyethyl)Trimethyl-Ammonium Chloride

CAS Number: 67-48-1 Molecular Formula: C5H14NOCl Molecular Weight: 139.63

Beilstein Registry Number: 3563126 EC Number: 200-655-4 MDL Number: MFCD00011721

SKU 02194639-CF
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Product Description

Choline chloride is an organic compound and a quaternary ammonium salt. It is a weak acid. Choline chloride is the salt of the naturally occurring choline, the pre-stage of the neurotransmitter acetylcholine, which is important for mnemonic and thought-processes. Choline occurs naturally in fungi, hop and kingcups and as integral part of lecithin. Choline chloride is a common food additive in animal husbandry

Application Notes

Choline chloride is used as a source of methyl groups for methyl-transfer reactions.

Key Applications

Choline acetyltransferase substrate

SKU 02194639-CF
Application Notes Choline chloride is used as a source of methyl groups for methyl-transfer reactions.
Beilstein Registry Number 3563126
Biochemical Physiological Actions The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes.
Density 1.1 g/cm3 at 20 °C (Lit.)
EC Number 200-655-4
Format Hard; White Crystalline Powder
Grade Cell Culture Reagent
Hazard Statements H315-H319-H335
Applications Choline acetyltransferase substrate
Melting Point 302-305 °C (dec.)(lit.)
Molecular Formula C5H14NOCl
Molecular Weight 139.63
Partition Coefficient n octanol/water (logKow): -3.77 at 25 °C (lit.)
Personal Protective Equipment Dust mask, Eyeshields, Gloves
pH Neutral to Litmus
Physical Appearance Hard; White Crystalline Powder
Purity >99%
RTECS Number KH2975000
Safety Symbol GHS08
Solubility Soluble in water: (10% aq soln) Clear, Colorless Solution.
Storage and Handling Store at Room Temperature (15-30 °C). Store Desiccated.
Vapor Pressure 10 hPa at 20 °C (Lit.)