Dino

L-Asparagine

L-Asparagine

Synonyms (S)-2-Aminosuccinic acid 4-amide; L-Aspartic acid 4-amide ; α-aminoauccinamic acid ; aspartic acid β-amide; Asn; N

CAS Number: 70-47-3 Molecular Formula: C4H8N2O3 Molecular Weight: 132.119 g/mol

Beilstein Registry Number: 1723527 EC Number: 200-735-9 MDL Number: MFCD00064401

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SKU 02194630-CF
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Description

Product Description

L-Asparagine

Application Notes

L-Asparagine is used in cell culture media and is a component of MEM non-essential amino acids solution. L-Asparagine has been shown to enhance ornithine decarboxylase activity in cultured human colon adenocarcinoma Caco-2 cells and in cultured IEC-6 intestinal epithelial cells. Spore germination in Bacillus subtilis has been increased in the presence of L-asparagine. An isoxazoline RGD mimic platelet GPIIb/IIIa antagonist has been prepared by chiral synthesis with L-asparagine as a starting material. L-Asparagine has been utilized in the synthesis of 4-azalysine building blocks for application to combinatorial chemistry.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Media component||Enhance ornithine decarboxylase activity||Increases spore germination

Specifications
SKU 02194630-CF
Application Notes L-Asparagine is used in cell culture media and is a component of MEM non-essential amino acids solution. L-Asparagine has been shown to enhance ornithine decarboxylase activity in cultured human colon adenocarcinoma Caco-2 cells and in cultured IEC-6 intestinal epithelial cells. Spore germination in Bacillus subtilis has been increased in the presence of L-asparagine. An isoxazoline RGD mimic platelet GPIIb/IIIa antagonist has been prepared by chiral synthesis with L-asparagine as a starting material. L-Asparagine has been utilized in the synthesis of 4-azalysine building blocks for application to combinatorial chemistry.
Beilstein Registry Number 1723527
Density 1.543 g/cu cm at 15/4 deg C
EC Number 200-735-9
Format powder
Grade Anhydrous; Cell Culture Reagent
Applications Media component||Enhance ornithine decarboxylase activity||Increases spore germination
Loss on Drying ≤1.0%
Melting Point 234-235 °C
Molecular Formula C4H8N2O3
Molecular Weight 132.119 g/mol
Optical Rotation +25° to +36° (c=10, 1N HCl)
Personal Protective Equipment Eyeshields, Gloves, respirator filter
Physical Appearance White Powder
pKa 2.14 (-COOH), 8.72 (-NH2)(Lit.)
Product Families Description L-Asparagine
Product Overview L-Asparagine
Purity ≥99%
Solubility Water Solubility29400 mg/L (at 25 °C)
Storage and Handling Store at Room Temperature (15-30 °C). Store Desiccated.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Vapor Pressure 4.8X10-8 mm Hg at 25 deg C (est)