Dino

β-Estradiol

β-Estradiol

Synonyms 1,3,5(10)-Estratriene-3,17β-diol; (17β)-Estra-1,3,5(10)-triene-3,17-diol; cis-estradiol; 3,17-epidihydroxyestratriene; dihydrofollicular hormone; dihydrofolliculin; dihydroxyestrin; dihydrotheelin; Dimenformon; Diogyn; Estrace; Estraderm; Estroclim; Evorel; Gynoestryl; Macrodiol; Menorest; Oestrogel; Ovocyclin; Ovocylin; Profoliol B; Progynon; Systen; Vagifem; Zumenon; 3,17β-Dihydroxy-1,3,5(10)-estratriene

CAS Number: 50-28-2 Molecular Formula: C18H24O2 Molecular Weight: 272.388 g/mol

Beilstein Registry Number: 1914275 EC Number: 200-023-8 MDL Number: MFCD00003693

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SKU 02194565-CF
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Description

Product Description

β-Estradiol

Application Notes

β-Estradiol is used to study cell differentiation and transformations (tumorigenicity).

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Tumorigenicity Studies

Specifications
SKU 02194565-CF
Application Notes β-Estradiol is used to study cell differentiation and transformations (tumorigenicity).
Beilstein Registry Number 1914275
Biochemical Physiological Actions The major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female phenotype in embryogenesis and during puberty by regulating gene transcription and, thus, protein synthesis. It also induces the production of gonadotropins which, in turn, induce ovulation. Exposure to estradiol increases breast cancer incidence and proliferation.
EC Number 200-023-8
Extinction Coefficient EM(280 nm) = 1950 (lit.)
Format powder
Grade Cell Culture Reagent
Hazard Statements H351-H360Fd-H362
Applications Tumorigenicity Studies
Melting Point 151-152
Molecular Formula C18H24O2
Molecular Weight 272.388 g/mol
Optical Rotation +76.8 (Concentration = 1, Solvent = Dioxane) (Lit.)
Personal Protective Equipment Eyeshields, Full-face particle respirator, Gloves, Respirator cartridge, Respirator filter
Physical Appearance White Powder
Product Families Description β-Estradiol
Product Overview β-Estradiol
RTECS Number KG2975000
Safety Symbol GHS08
Solubility Water Solubility3.6 mg/L (at 27 °C)
Storage and Handling Store at Room Temperature (15-30 °C). Store under nitrogen.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Vapor Pressure 6.38X10-9 mm Hg at 25 deg C (est)