Dexamethasone

Dexamethasone

Synonyms (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione; 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione; 9α-Fluoro-16α-methylprednisolone; Prednisolone F; 9-Fluoro-11β,17,21-trihydroxy-16α- methylpregna- 1,4-diene-3,20-dione; hexadecadrol; Aeroseb-Dex; Corson; Cortisumman; Decacort; Decaderm; Decadron; Decalix; Decasone; Dekacort; Deltafluorene; Deronil; Deseronil; Dexacortal; Dexacortin; Dexafarma; Dexa-Mamallet; Dexameth; Dexamonozon; Dexapos; Dexa-sine; Dexasone; Dexinoral; Dinormon; Fluormone; Isopto-Dex; Lokalison F; Loverine; Luxazone; Maxidex; Millicorten

CAS Number: 50-02-2 Molecular Formula: C22H29FO5 Molecular Weight: 392.467 g/mol

Beilstein Registry Number: 2066651 EC Number: 200-003-9 MDL Number: MFCD00064136

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SKU 02194561-CF
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Description

Product Description

Dexamethasone

Application Notes

Dexamethasone is an anti-inflammatory glucocorticoid with a range of effects on cell survival, cell signaling and gene expression. It is used to study apoptosis, cell signaling pathways and gene expression.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Anti-inflammatory

Specifications
SKU 02194561-CF
Alternate Names (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione; 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione; 9α-Fluoro-16α-methylprednisolone; Prednisolone F; 9-Fluoro-11β,17,21-trihydroxy-16α- methylpregna- 1,4-diene-3,20-dione; hexadecadrol; Aeroseb-Dex; Corson; Cortisumman; Decacort; Decaderm; Decadron; Decalix; Decasone; Dekacort; Deltafluorene; Deronil; Deseronil; Dexacortal; Dexacortin; Dexafarma; Dexa-Mamallet; Dexameth; Dexamonozon; Dexapos; Dexa-sine; Dexasone; Dexinoral; Dinormon; Fluormone; Isopto-Dex; Lokalison F; Loverine; Luxazone; Maxidex; Millicorten
Application Notes Dexamethasone is an anti-inflammatory glucocorticoid with a range of effects on cell survival, cell signaling and gene expression. It is used to study apoptosis, cell signaling pathways and gene expression.
Beilstein Registry Number 2066651
Biochemical Physiological Actions Glucocorticoid anti-inflammatory agent. It Regulates T cell survival, growth, and differentiation. It also inhibits the induction of nitric oxide synthase.
Boiling Point Decomposes
Density 1.85
EC Number 200-003-9
Format powder
Grade Cell culture reagent
Hazard Statements H315-H317-H319-H334-H335
Applications Anti-inflammatory
Loss on Drying ≤0.5%
MDL # MFCD00064136
Melting Point 504 to 507° F (NTP, 1992)
Molecular Formula C22H29FO5
Molecular Weight 392.467 g/mol
Optical Rotation (c=1, dioxane)+72 ° to +80 °
Personal Protective Equipment Dust mask, Eyeshields, Faceshields, Gloves
Physical Appearance White Powder
Product Families Description Dexamethasone
Product Overview Dexamethasone
Refractive Index 76 ° (C=1; Dioxane) (Lit.)
RTECS Number TU3980000
Safety Symbol GHS07, GHS08
Solubility less than 1 mg/mL at 77° F (NTP, 1992)
Storage and Handling Store at Room Temperature (15-30 °C); protect from light.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Vapor Pressure 8.86X10-14 mm Hg at 25 deg C (est)