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Streptomycin Sulfate, PhytoPure™

Streptomycin Sulfate, PhytoPure™

Synonyms Streptomycin Sesquisulfate; O-2-Deoxy-2-(methylamino)-a-L- glucopyranosyl-(1->2)-O-5-deoxy-3-C-formyl-a-L-lyxofuranosyl- (1->4)- N,N'- bis(aminoiminomethyl)-D-streptamine; Streptomycin A

CAS Number: 3810-74-0 Molecular Formula: 2C21H39N7O12-3H2SO4 Molecular Weight: 1457.40

Beilstein Registry Number: 3894995 EC Number: 223-286-0 MDL Number: MFCD00037023

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SKU 02194541-CF
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Description

Product Description

An aminoglycoside antimycobacterial effective against both gram-negative and gram-positive bacteria. Widely used in combination with penicillin in a standard antibiotic cocktail to prevent bacterial infection in cell culture. Streptomycin controls bacterial and fungal diseases of certain fruit, vegetables, seed and ornamental crops.

Application Notes

Streptomycin, in combination with penicillin, is used in a standard antibiotic cocktail to prevent bacterial infection in cell culture. Streptomycin also is used as a pesticide, to combat the growth of bacteria, fungi, and algae. Streptomycin controls bacterial and fungal diseases of certain fruit, vegetables, seed, and ornamental crops, and it controls algae in ornamental ponds and aquaria.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Antibiotic||Pesticide||Cell culture||Treatment of Tuberculosis; Plague

Specifications
SKU 02194541-CF
Application Notes Streptomycin, in combination with penicillin, is used in a standard antibiotic cocktail to prevent bacterial infection in cell culture. Streptomycin also is used as a pesticide, to combat the growth of bacteria, fungi, and algae. Streptomycin controls bacterial and fungal diseases of certain fruit, vegetables, seed, and ornamental crops, and it controls algae in ornamental ponds and aquaria.
Beilstein Registry Number 3894995
Biochemical Physiological Actions Mode of Action: Inhibits prokaryote protein synthesis by preventing the transition from initiation complex to chain-elongating ribosome and casues miscoding: Binds to S12 protein of 30S ribosomal subunit causing the misreading or the inhibition of initiation. Mode of Resistance: Mutation in rpsL (gene for S12 ribosomal protein) prevents binding of streptomycin to ribosome. Aminoglycoside phosphotransferase also inactivates. Inactivation: Streptomycin is inactivated by acids, alkalis, oxidizing and reducing agents, urea and other carbonyl-containing compounds, as well as by cysteine and other sulfhydryl-containing substances. Loss in potency was reported. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
EC Number 223-286-0
Format Sulfate Salt; Powder
Grade Cell Culture Reagent
Half Life The half-life in plasma is about 2-4 hours.
Hazard Statements H302-H361
Applications Antibiotic||Pesticide||Cell culture||Treatment of Tuberculosis; Plague
Loss on Drying ≤7.0%
Molecular Formula 2C<sub>21</sub>H<sub>39</sub>N<sub>7</sub>O<sub>12</sub>-3H<sub>2</sub>SO<sub>4</sub>
Molecular Weight 1457.40
Personal Protective Equipment Dust mask, Eyeshields, Faceshields, Gloves
Physical Appearance White Powder
Product Families Description Streptomycin sulfate
Product Overview Streptomycin Sulphate
RTECS Number WK4990000
Safety Symbol GHS07, GHS08
Solubility greater than or equal to 0.1 mg/mL at 64° F (NTP, 1992)
Specific Activity ≥650 u/mg
Sterilization of Solutions Stock solututions should be sterile filtered.
Storage and Handling Stored at +4 °C; protect from light
Typical Working Concentration Typically used at a concentration of 50-100 mg/liter.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.