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Paromomycin Sulfate, PhytoPure™

Paromomycin Sulfate, PhytoPure™

CAS Number: 1263-89-4 Molecular Formula: C23H45N5O14-H2SO4 Molecular Weight: 713.70

Beilstein Registry Number: 5715182 EC Number: 215-031-7 MDL Number: MFCD00079278

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SKU 02194535-CF
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Description

Product Description

An aminoglycoside antibiotic effective against gram-negative bacteria. Like neomycin, it inhibits protein synthesis by binding to 16s-ribosomal RNA. Useful in studies of cytosine-cytosine (CC) mismatch containing RNAs.

Application Notes

Paromomycin sulfate salt has been used as a• reference compound in antileishmanial activity• RNA-binding ligand and interacts with aptamer. This interaction prevents the binding (and cutting) of dicer to RNA duplex

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Antibiotic

Specifications
SKU 02194535-CF
Application Notes Paromomycin sulfate salt has been used as a• reference compound in antileishmanial activity• RNA-binding ligand and interacts with aptamer. This interaction prevents the binding (and cutting) of dicer to RNA duplex
Beilstein Registry Number 5715182
Biochemical Physiological Actions Paromomycin inhibits the initiation and elongation steps of protein synthesis by binding to 16S ribosomal RNA. Paramomycin binds to the A site, which causes defective polypeptide chains to be produced and leads to cell death.
EC Number 215-031-7
Format powder
Grade Cell culture reagent
Applications Antibiotic
Molecular Formula C<sub>23</sub>H<sub>45</sub>N<sub>5</sub>O<sub>14</sub>-H<sub>2</sub>SO<sub>4</sub>
Molecular Weight 713.70
Physical Appearance White Powder
Potency >675 µg/mg
Product Families Description Paromomycin sulfate
Product Overview Paromomycin Sulfate
Purity ≥97%
RTECS Number WK2320000
Storage and Handling Store at Room Temperature (15-30 °C).
Typical Working Concentration Paromomycin sulfate is recommended for use in cell culture applications at 100 mg/L.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.