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Nystatin, PhytoPure™

Nystatin, PhytoPure™

Synonyms Mycostatin;Fungicidin

CAS Number: 1400-61-9 Molecular Formula: C47H75NO17 Molecular Weight: 926.10

EC Number: 215-749-0

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SKU 02194534-CF
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Description

Product Description

A polyene antifungal effective against molds, fungi and yeast contamination. It binds to ergosterol and creates nystatin/ergosterol based ion channels in lipid bilayers causing K+ leakage that results in fungal cell death.

Application Notes

Nystatin is a polyene antibiotic. Its uses include preventing cell culture contamination and inducing interleukin (IL)-1, IL-8, and tumor necrosis factor a secretion in TLR2-expressing THP1 cells.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Antibiotic

Specifications
SKU 02194534-CF
Application Notes Nystatin is a polyene antibiotic. Its uses include preventing cell culture contamination and inducing interleukin (IL)-1, IL-8, and tumor necrosis factor a secretion in TLR2-expressing THP1 cells.
Biochemical Physiological Actions Mode of Action: Nystatin acts by binding to ergosterols in fungal cell membranes, increasing permeability of the membrane, and creating nystatin/ergosterol based ion channels. It also functions as a lipid raft-inhibiting reagent and as membrane associated cholesterol.Antimicrobial spectrum: Neomycin acts against fungi, yeasts and molds.
EC Number 215-749-0
Format powder
Grade Cell Culture Reagent
Applications Antibiotic
Loss on Drying <8%
Molecular Formula C<sub>47</sub>H<sub>75</sub>NO<sub>17</sub>
Molecular Weight 926.10
Personal Protective Equipment Eyeshields, Gloves, Respirator filter
Physical Appearance Dark Orangish Yellow Powder
Product Families Description Nystatin
Product Overview Nystatin
RTECS Number RF5950000
Specific Activity >5000 u/mg
Storage and Handling Store at + 4 °C. Protect from light.
Typical Working Concentration 50 mg/L for yeasts and fungi.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
UV Visible Absorbance 290, 305, 320 ± 2 nm( λ max (ethanol))