Dino

Gentamycin Sulfate, PhytoPure™

Gentamycin Sulfate, PhytoPure™

Synonyms Garamycin; Genoptic; GM Sulfate;Gentiomycin C

CAS Number: 1405-41-0 Molecular Formula: C21H43N5O7-H2SO4 Molecular Weight: 575.70

EC Number: 215-778-9 MDL Number: MFCD00270181

Configure Your Product:

SKU 02194530-CF
Price:
$19.40
In Stock
Request a quote
Description

Product Description

A bactericidal aminoglycoside antibiotic predominantly active against gram-negative bacteria. It disrupts protein synthesis at the 30S ribosome. Used as a selection agent (gentamicin-resistance gene) in cell culture and molecular biology applications. Approximately 600 µg gentamycin per mg.

Application Notes

Gentamicin sulfate is a broad spectrum antibiotic. It inhibits the growth of a wide variety of Gram-positive and Gram-negative microorganisms, including strains resistant to tetracycline, chloramphenicol, kanamycin, and colistin, particularly strains of Pseudomonas, Proteus, Staphylococcus, and Streptococcus. Gentamicin sulfate inhibits bacterial protein biosynthesis by binding to the 30S subunit of the ribosome.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Specifications
SKU 02194530-CF
Application Notes Gentamicin sulfate is a broad spectrum antibiotic. It inhibits the growth of a wide variety of Gram-positive and Gram-negative microorganisms, including strains resistant to tetracycline, chloramphenicol, kanamycin, and colistin, particularly strains of Pseudomonas, Proteus, Staphylococcus, and Streptococcus. Gentamicin sulfate inhibits bacterial protein biosynthesis by binding to the 30S subunit of the ribosome.
Biochemical Physiological Actions Mode of action: Gentamicin causes codon misreading by binding to the 30S ribosomal subunit, blocking the translocation of peptidyl-tRNA from the acceptor site to the donor site.The bactericidal effect of gentamicin on Pseudomonas aeruginosa is exerted by the binding of gentamicin to the outer membrane, where it displaces natural cations, destabilizes the membrane, and forms holes in the cell surface.Antimicrobial spectrum: Gram-negative bacteria, Staphylococcus aureus and other Gram-positive bacteria.
EC Number 215-778-9
Grade Cell Culture Reagent
Hazard Statements H317-H334
Molecular Formula C<sub>21</sub>H<sub>43</sub>N<sub>5</sub>O<sub>7</sub>-H<sub>2</sub>SO<sub>4</sub>
Molecular Weight 575.70
Optical Rotation +116°
Personal Protective Equipment Dust mask type , Eyeshields, Faceshields, Gloves
Physical Appearance White Powder
Potency >590 µg/mg
Product Families Description Gentamicin sulfate
Product Overview Gentamicin Sulfate
RTECS Number LY2625000
Safety Symbol GHS08
Storage and Handling Store at +4 °C.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.