Dino

Colistin Sulphate Salt

Colistin Sulphate Salt

Synonyms Polymyxin E

CAS Number: 1264-72-8 Molecular Weight: 1253.527 g/mol

EC Number: 215-034-3 MDL Number: MFCD00146495

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SKU 02194157-CF
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Description

Product Description

Colistin Sulphate Salt

Application Notes

Colistin sulfate is used to permeabilize bacterial cell membranes and to study mannose-resistant haemagglutination and antibiotic resistance in certain organisms such as A. baumannii. It has been used to study hephrotoxicity in the rat kidney, and MICs, time-kill kinetics, and postantibiotic effect (PAE) against Pseudomonas aeruginosa.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Specifications
SKU 02194157-CF
Application Notes Colistin sulfate is used to permeabilize bacterial cell membranes and to study mannose-resistant haemagglutination and antibiotic resistance in certain organisms such as A. baumannii. It has been used to study hephrotoxicity in the rat kidney, and MICs, time-kill kinetics, and postantibiotic effect (PAE) against Pseudomonas aeruginosa.
Biochemical Physiological Actions Mode of Action: Binds to lipids on the cell cytoplasmic membrane of Gram-negative bacteria and disrupts the cell wall integrity. Antimicrobial spectrum: Gram-negative bacteria. It is proposed that renal reabsorption of colistin may involve organic cation transporters and peptide transporters and that the process is sensitive to pH.
EC Number 215-034-3
Hazard Statements H301
Molecular Weight 1253.527 g/mol
Personal Protective Equipment Eyeshields, Faceshields, Gloves, respirator cartridges
Physical Appearance Off-white powder
Product Families Description Colistin
Product Overview Colistin Sulphate Salt
RTECS Number TR1500000
Specific Activity ≥15,000 u/mg
Storage and Handling +4 °C; desiccate
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.