Miconazole

Miconazole

Synonyms 1-[2,4-Dichloro-β-([2,4-dichlorobenzyl]oxy)phenethyl]imidazole; 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole; Monistat; Daktarin IV; Miconazolo; Miconazolum; Dactarin; Miconazol; Minostate; Brentan; Florid(nitrate)

CAS Number: 22916-47-8 Molecular Formula: C18H14Cl4N2O Molecular Weight: 416.123 g/mol

EC Number: 245-324-5

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SKU 02193915-CF
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Description

Product Description

Miconazole

Application Notes

Miconazole is an imidazole antifungal agent that is used topically and by intravenous infusion. It is used to inhibit cytochrome P450 and to study automated luminescence-based cytochrome P450 profiling

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Anti-fungal agent

Specifications
SKU 02193915-CF
Alternate Names 1-[2,4-Dichloro-β-([2,4-dichlorobenzyl]oxy)phenethyl]imidazole; 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole; Monistat; Daktarin IV; Miconazolo; Miconazolum; Dactarin; Miconazol; Minostate; Brentan; Florid(nitrate)
Application Notes Miconazole is an imidazole antifungal agent that is used topically and by intravenous infusion. It is used to inhibit cytochrome P450 and to study automated luminescence-based cytochrome P450 profiling
Biochemical Physiological Actions Miconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary for ergosterol biosynthesis. The inhibition of ergosterol results in increased cellular permeability causing leakage of cellular contents. Miconazole may also inhibit endogenous respiration, interact with phospholipids in the cell membrane, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and interfere with triglyceride and phospholipid biosynthesis.
EC Number 245-324-5
Format powder
Applications Anti-fungal agent
Melting Point 159-163 °C
Molecular Formula C18H14Cl4N2O
Molecular Weight 416.123 g/mol
Physical Appearance White Powder
Product Families Description Miconazole
Product Overview Miconazole
RTECS Number NI4770000
Solubility Water Solubility1g/100mL (20 °C)
Storage and Handling Room Temperature
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.