4-(2-Aminoethyl)Benzenesulfonyl Fluoride Hydrochloride

4-(2-Aminoethyl)Benzenesulfonyl Fluoride Hydrochloride

Synonyms AEBSF; 4-(2-Aminoethyl)-Benzenesulfonyl Fluoride Hydrochloride; p-Aminoethylbenzenenesulfonyl fluoride

CAS Number: 30827-99-7 Molecular Formula: C8H10FNO2S • HCl Molecular Weight: 239.689 g/mol

Beilstein Registry Number: 7604627 MDL Number: MFCD00132962

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SKU 02193503-CF
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Description

Product Description

4-(2-Aminoethyl)Benzenesulfonyl Fluoride Hydrochloride

Application Notes

The lower molecular weight and toxicity of AEBSF relative to PMSF and related organophosphate inhibitors, make this inhibitor well suited for blocking trypsin-like activities in tissue culture media as well as in large scale purification of recombinant proteins , susceptible to proteolysis

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Inhibitor||Serine Protease Inhibitors||Trypsin Inhibitors

Specifications
SKU 02193503-CF
Alternate Names AEBSF; 4-(2-Aminoethyl)-Benzenesulfonyl Fluoride Hydrochloride; p-Aminoethylbenzenenesulfonyl fluoride
Application Notes The lower molecular weight and toxicity of AEBSF relative to PMSF and related organophosphate inhibitors, make this inhibitor well suited for blocking trypsin-like activities in tissue culture media as well as in large scale purification of recombinant proteins , susceptible to proteolysis
Beilstein Registry Number 7604627
Biochemical Physiological Actions Irreversible serine protease inhibitor. Inhibition constants are similar to those of PMSF and DFP. AEBSF has been shown to inhibit trypsin, chymotrypsin, plasmin kallikrein and thrombin. As an alternative to PMSF and DFP, AEBSF offers lower toxicity, improved solubility in water and improved stability in aqueous solutions.
Format White powder
Hazard Statements H314
Applications Inhibitor||Serine Protease Inhibitors||Trypsin Inhibitors
MDL # MFCD00132962
Molecular Formula C8H10FNO2S • HCl
Molecular Weight 239.689 g/mol
Physical Appearance White powder
Product Families Description 4-(2-Aminoethyl)benzenesulfonyl fluoride
Product Overview 4-(2-Aminoethyl)Benzenesulfonyl Fluoride Hydrochloride
Purity ≥97%
Safety Symbol GHS05
Storage and Handling Store at Room Temperature and protect from light.
Typical Working Concentration AEBSF has been used in cell culture in concentrations of up to 0.25 mM.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.