4-(2-Aminoethyl)Benzenesulfonyl Fluoride Hydrochloride
Product Description
4-(2-Aminoethyl)Benzenesulfonyl Fluoride Hydrochloride
Application Notes
The lower molecular weight and toxicity of AEBSF relative to PMSF and related organophosphate inhibitors, make this inhibitor well suited for blocking trypsin-like activities in tissue culture media as well as in large scale purification of recombinant proteins , susceptible to proteolysis
Usage Statement
Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Key Applications
Inhibitor||Serine Protease Inhibitors||Trypsin Inhibitors
| SKU | 02193503-CF |
| Alternate Names | AEBSF; 4-(2-Aminoethyl)-Benzenesulfonyl Fluoride Hydrochloride; p-Aminoethylbenzenenesulfonyl fluoride |
| Application Notes | The lower molecular weight and toxicity of AEBSF relative to PMSF and related organophosphate inhibitors, make this inhibitor well suited for blocking trypsin-like activities in tissue culture media as well as in large scale purification of recombinant proteins , susceptible to proteolysis |
| Beilstein Registry Number | 7604627 |
| Biochemical Physiological Actions | Irreversible serine protease inhibitor. Inhibition constants are similar to those of PMSF and DFP. AEBSF has been shown to inhibit trypsin, chymotrypsin, plasmin kallikrein and thrombin. As an alternative to PMSF and DFP, AEBSF offers lower toxicity, improved solubility in water and improved stability in aqueous solutions. |
| Format | White powder |
| Hazard Statements | H314 |
| Applications | Inhibitor||Serine Protease Inhibitors||Trypsin Inhibitors |
| MDL # | MFCD00132962 |
| Molecular Formula | C8H10FNO2S • HCl |
| Molecular Weight | 239.689 g/mol |
| Physical Appearance | White powder |
| Product Families Description | 4-(2-Aminoethyl)benzenesulfonyl fluoride |
| Product Overview | 4-(2-Aminoethyl)Benzenesulfonyl Fluoride Hydrochloride |
| Purity | ≥97% |
| Safety Symbol | GHS05 |
| Storage and Handling | Store at Room Temperature and protect from light. |
| Typical Working Concentration | AEBSF has been used in cell culture in concentrations of up to 0.25 mM. |
| Usage Statement | Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |