Complement C1Q Protein

Complement C1Q Protein

CAS Number: 80295-33-6

MDL Number: MFCD00130851

Packaging size: 1 mL

SKU 0219139101
Price:
$516.00
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Description

Product Description

Complement C1Q Protein

Application Notes

Complement component C1q is an important regulator factor for platelet activation. This has been a topic for research, as platelet-leukocyte aggregates play an important role in inflammatory conditions such as coronary heart disease. In particular, C1q has been shown to inhibit collagen induced aggregation and enhance production of reactive oxygen species (ROS).

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Platelet activation

Specifications
SKU 0219139101
Application Notes Complement component C1q is an important regulator factor for platelet activation. This has been a topic for research, as platelet-leukocyte aggregates play an important role in inflammatory conditions such as coronary heart disease. In particular, C1q has been shown to inhibit collagen induced aggregation and enhance production of reactive oxygen species (ROS).
Biochemical Physiological Actions C1q deficiency, either because of rare homozygous genetic defect, or transcriptional/translational defects, is almost certainly a cause of systemic lupus erythematosus (SLE). The three C1q subunits are expressed through a novel mechanism of transcriptional synchronization.
Format liquid
Formulation Supplied in HEPES; 40% glycerol; 40% glycerol.
Gene ID human ... C1QA(712), C1QB(713), C1QC(714)
Hazard Statements H317
Applications Platelet activation
MDL # MFCD00130851
Pack Size 1 mL
Physical Appearance Colorless Liquid
Product Families Description Complement C1q protein
Product Overview Complement C1Q Protein
Source Human serum
Storage and Handling Store at -70 °C. Avoid repeat freeze/thaw.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.