Chlorhexidine

Chlorhexidine

Synonyms 1,6-Di(N-p-chlorophenyl- diguanido) hexane ; 1,6-Di(N-p-Chlorophenyldiguanido) hexane; 1,1'-Hexamethylene bis[5-(4- chlorophenyl) biguanide]

CAS Number: 55-56-1 Molecular Formula: C22H30Cl2N10 Molecular Weight: 505.452 g/mol

Beilstein Registry Number: 2826432 EC Number: 200-238-7 MDL Number: MFCD00009673

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SKU 02191358-CF
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Description

Product Description

Chlorhexidine

Application Notes

An intermediate for the production of chlorhexidine salts which are used as an antiseptic and disinfectant agent. It is effective against a wide range of bacteria, some fungi and some viruses, and an agent for the prevention of gingivitis. Commercial ophthalmic products have used this agent to replace thimerosal as a preservative; however, it can cause skin irritation. It ia used in analytical standard for pharmaceuticals.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Antiseptic||Disinfectant agent||Chemical Synthesis

Specifications
SKU 02191358-CF
Alternate Names 1,6-Di(N-p-chlorophenyl- diguanido) hexane ; 1,6-Di(N-p-Chlorophenyldiguanido) hexane; 1,1'-Hexamethylene bis[5-(4- chlorophenyl) biguanide]
Application Notes An intermediate for the production of chlorhexidine salts which are used as an antiseptic and disinfectant agent. It is effective against a wide range of bacteria, some fungi and some viruses, and an agent for the prevention of gingivitis. Commercial ophthalmic products have used this agent to replace thimerosal as a preservative; however, it can cause skin irritation. It ia used in analytical standard for pharmaceuticals.
Beilstein Registry Number 2826432
EC Number 200-238-7
Format powder
Hazard Statements H315-H319-H334-H335-H410
Applications Antiseptic||Disinfectant agent||Chemical Synthesis
MDL # MFCD00009673
Melting Point 258-260
Molecular Formula C22H30Cl2N10
Molecular Weight 505.452 g/mol
Personal Protective Equipment Dust mask , Eyeshields, Faceshields, Gloves
Physical Appearance Off-White Powder
Product Families Description Chlorhexidine
Product Overview Chlorhexidine
Residue on Ignition ≤0.2%
RTECS Number DU1925000
Safety Symbol GHS07, GHS08, GHS09
Solubility Water Solubility800 mg/L (at 20 °C)
Sterilization of Solutions Dilute solutions of chlorhexidine (<1.0% w/v) may be sterilized by autoclaving at 115 °C for 30 minutes or at 121-123 °C for 15 minutes. Autoclaving of solutions greater than 1.0% can result in the formation of insoluble residues and is therefore unsuitable. If sterile solutions are required at such high concentrations, then filtration through a 0.22 um membrane filter is recommended. Dilute chlorhexidine solutions may be stored at room temperature, and a shelf life of at least 1 year can be expected, provided that the packaging is adequate. Prolonged exposure to high temperature or light is to be avoided because this can adversely affect the stability of chlorhexidine solutions. All dilute solutions to be stored should be either heat-treated (sterilized or pasteurized) or chemically preserved (4 % isopropanol or 7 % ethanol) to eliminate the possibility of microbial contamination. .
Storage and Handling +4°C
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.
Vapor Pressure 1.98X10-14 mm Hg at 25 deg C (est)