Albumin, Human

Albumin, Human

Synonyms HSA

CAS Number: 70024-90-7 Molecular Weight: 188.02 g/mol

EC Number: 274-272-6 MDL Number: MFCD00081418

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SKU 02191349-CF
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Description

Product Description

Albumin, Human

Application Notes

The main biological function of albumin is to regulate the colloidal osmotic pressure of blood. Human and bovine albumins contain 16% nitrogen and are often used as standards in protein calibration studies. Due to their free hydrophobic region fatty acid free albumins are used to solubilize lipids in tissue culture, and are also used as blocking agents in Western blots or ELISA applications. Globulin free albumins are suitable for use in applications where no other proteins should be present (e.g., electrophoresis).

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Carrier protein

Specifications
SKU 02191349-CF
Alternate Names HSA
Analysis Note Each donor unit used in the manufacture of this product was tested by an FDA approved method for the presence of antibody to HIV 1/2, antibody to HCV, HIV-Ag, as well as for the Hepatitis B Surface Antigen (HBsAg), and found to be negative (not repeatably reactive).
Application Notes The main biological function of albumin is to regulate the colloidal osmotic pressure of blood. Human and bovine albumins contain 16% nitrogen and are often used as standards in protein calibration studies. Due to their free hydrophobic region fatty acid free albumins are used to solubilize lipids in tissue culture, and are also used as blocking agents in Western blots or ELISA applications. Globulin free albumins are suitable for use in applications where no other proteins should be present (e.g., electrophoresis).
Biochemical Physiological Actions Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influence their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has widely varied effects on its physiological function.
Boiling Point -36.6 °C
Density 1.352 at 20 deg C (liquid)
EC Number 274-272-6
Format Crystal-like Powder
Gene ID Human ALB(213)
Isoelectric Point 4.7 (?/2 = 0.15) (Lit.)
Applications Carrier protein
MDL # MFCD00081418
Melting Point -147.6 °C
Molecular Weight 188.02 g/mol
Personal Protective Equipment Eyeshields, Gloves
Physical Appearance Off-white Crystal-like Powder
Product Families Description Albumin
Product Overview Albumin, Human
Purity >97%
Solubility Water Solubility5.7 mg/L (at 15 °C)
Source Human
Storage and Handling Store at +4 °C.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.
Vapor Pressure 6.63X10+3 mm Hg at 25 deg C