Dino

Cathepsin G

Cathepsin G

Synonyms E.C. 3.4.21.20

CAS Number: 107200-92-0

MDL Number: MFCD00130750

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SKU 02191344-CF
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Description

Product Description

Cathepsin G

Application Notes

Cathepsin G act as a bacteriocidal reagent. Catrhepsin G is often referred to as a chymotrypsin-like enzyme, since it preferentially cleaves proteins on the carboxyl side of leucine, methionine, and phenylalanine. Cathepsin G can be assayed with substrates such as azocasein, Suc-Ala-Ala-Pro-Phe-NPhNO2, and MeOSUC-Ala-Ala-Pro-Met-NPh-NO2. Cathepsin G also has a specificity of action on the oxidized B chain of insulin and on BSA, which indicates a closer similarity to porcine chymotrypsin C than to bovine chymotrypsin A.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Enzymes||Inhibitors||Substrates

Specifications
SKU 02191344-CF
Application Notes Cathepsin G act as a bacteriocidal reagent. Catrhepsin G is often referred to as a chymotrypsin-like enzyme, since it preferentially cleaves proteins on the carboxyl side of leucine, methionine, and phenylalanine. Cathepsin G can be assayed with substrates such as azocasein, Suc-Ala-Ala-Pro-Phe-NPhNO2, and MeOSUC-Ala-Ala-Pro-Met-NPh-NO2. Cathepsin G also has a specificity of action on the oxidized B chain of insulin and on BSA, which indicates a closer similarity to porcine chymotrypsin C than to bovine chymotrypsin A.
Biochemical Physiological Actions Cathepsin G has pro-apoptotic activity and can activate caspases in vitro.
Format powder
Applications Enzymes||Inhibitors||Substrates
Physical Appearance White Powder
Product Families Description Cathepsin G
Product Overview Cathepsin G
Purity ≥95%
Source Human Neutrophils
Specific Activity 2 - 4 μ/mg protein
Storage and Handling Store at -70 °C.
Unit Definition The amount of enzyme that hydrolyzes one µmole of Suc-ala-ala-pro-phe-pNA (1mM) per minute 25 °C in pH 7.5, with 1.6 M NaCl.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.