Dino

Aprotinin

Aprotinin

Synonyms Antagosan; Anikrein; Antilysin(e); Basic pancreatic trypsin inhibitor; BPTI; Bayer A 128; Kallikrein-trypsin inactivator; Fosten; Iniprol; Kunitz protease inhibitor; Onquinin; Repulson; RP-9921; Ryker 52G; Trasylol; Triazinin; Zymofren

CAS Number: 9087-70-1 Molecular Formula: C284H432N84O79S7 Molecular Weight: 6511.509 g/mol

EC Number: 232-994-9 MDL Number: MFCD00130541

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SKU 02191158-CF
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Description

Product Description

Aprotinin

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Competitive serine protease inhibitor

Specifications
SKU 02191158-CF
Biochemical Physiological Actions Aprotinin is a competitive serine protease inhibitor that inhibits trypsin, chymotrypsin, kallikrein and plasmin. Aprotinin forms stable complexes with and blocks the active sites of enzymes. Binding is reversible with most aprotinin-protease complexes dissociating at pH >10 or < 3.
EC Number 232-994-9
Extinction Coefficient E1% (280 nm) = 8.3 (water)
Format lyophilized powder
Isoelectric Point 10.5
Applications Competitive serine protease inhibitor
Melting Point >100 °C
Molecular Formula C284H432N84O79S7
Molecular Weight 6511.509 g/mol
Physical Appearance White Powder
Product Families Description Aprotinin
Product Overview Aprotinin
RTECS Number YN5080000
Source Bovine Lung
Specific Activity ~4 inhibitor u/mg
Sterilization of Solutions Sterilization of solutions can be done by filtration through a 0.2 um filter.
Storage and Handling Store at +4 °C.
Typical Working Concentration Equimolar with protease (1-2 ug/ml)
Unit Definition The quantity of protease inhibitor that has the ability to inhibit 2 Kallikrein units by 50% under optimal conditions.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
UV Visible Absorbance 277 ± 5 nm (1 max water)