Forskolin

Forskolin

Synonyms 7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-one; Coleonol; Colforsin

CAS Number: 66575-29-9 Molecular Formula: C22H34O7 Molecular Weight: 410.507 g/mol

Beilstein Registry Number: 1692716 EC Number: 266-410-9 MDL Number: MFCD00082317

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SKU 02190669-CF
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Description

Product Description

Forskolin

Application Notes

Forkolin is reported to demonstrate positive inotropic and heart rate-increasing activity at low doses in animals. Also functions as an antihypertensive and vasodilator at higher doses. Activates adenylcyclase in rat liver membranes.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Antihypertensive||Vasodilator

Specifications
SKU 02190669-CF
Alternate Names 7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-one; Coleonol; Colforsin
Application Notes Forkolin is reported to demonstrate positive inotropic and heart rate-increasing activity at low doses in animals. Also functions as an antihypertensive and vasodilator at higher doses. Activates adenylcyclase in rat liver membranes.
Beilstein Registry Number 1692716
Biochemical Physiological Actions Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration. Forskolin effects calcium currents and inhibits MAP kinase.
EC Number 266-410-9
Hazard Statements H312
Applications Antihypertensive||Vasodilator
MDL # MFCD00082317
Molecular Formula C22H34O7
Molecular Weight 410.507 g/mol
Personal Protective Equipment Dust mask type , Eyeshields, Gloves
Physical Appearance White Powder
Product Families Description Forskolin
Product Overview Forskolin
RTECS Number QL6150000
Safety Symbol GHS07
Source Coleus forskohlii
Storage and Handling -20 °C; dessicate
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.