Chlortetracycline Hydrochloride

Chlortetracycline Hydrochloride

Synonyms Aureomycin; Chlorotetracycline hydrochloride; 7-Chlorotetracycline hydrochloride; aureocycline; auxeomycin; biomycin; 7-chlorotetracycline

CAS Number: 64-72-2 Molecular Formula: C22H23ClN2O8 • HCl Molecular Weight: 515.34 g/mol

Beilstein Registry Number: 3858364 EC Number: 200-591-7 MDL Number: MFCD00082440

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SKU 02190327-CF
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Description

Product Description

Chlortetracycline Hydrochloride

Application Notes

Cell-permeable fluorescent probe for Ca2+ for measuring calcium flux in endoplasmic reticulum and other intracellular stores in situ.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Antibacterial||Antibiotics

Specifications
SKU 02190327-CF
Alternate Names Aureomycin; Chlorotetracycline hydrochloride; 7-Chlorotetracycline hydrochloride; aureocycline; auxeomycin; biomycin; 7-chlorotetracycline
Application Notes Cell-permeable fluorescent probe for Ca2+ for measuring calcium flux in endoplasmic reticulum and other intracellular stores in situ.
Beilstein Registry Number 3858364
Biochemical Physiological Actions Chlortetracycline is an antibiotic produced by some strains of Streptomyces aureofaciens. Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-positive. Less active against Gram-negative bacterial than tetracycline. Mode of Resistance: Loss of cell wall permeability.
EC Number 200-591-7
Format powder
Hazard Statements H315-H319-H335
Heavy Metals <100 ppm
Applications Antibacterial||Antibiotics
MDL # MFCD00082440
Molecular Formula C22H23ClN2O8 • HCl
Molecular Weight 515.34 g/mol
Personal Protective Equipment Dust mask , Eyeshields, Gloves
Physical Appearance Yellow Powder
pKa 3.3, 7.4 and 9.3 at 25 °C.(Lit.)
Preparation Method To prepare Stock Solutions: Add the appropriate amount of powder to water while mixing (not the reverse), as adding water to the powders may result in insoluble mixtures that cannot be filtered without losing potency. If desired, the pH may be adjusted, but a basal media with greater than 2 g/L sodium bicarbonate can easily absorb up to 2 % of an acidic antibiotic solution; therefore, an antibiotic solution with an acidic pH would not influence the pH of the media. After ensuring that the resultant solution is transparent, sterile filter and store in small aliquots at appropriate temperature until use. Prior to use of the media, aseptically add the appropriate amount of antibiotic to the basal media in order to obtain the required working concentration. Mix well and sterile filter if asepsis is believed to have been compromised.
Product Families Description Chlortetracycline
Product Overview Chlortetracycline Hydrochloride
RTECS Number QI7800000
Safety Symbol GHS07
Specific Activity >900 u/mg
Sterilization of Solutions Solutions should be filter sterilized. Store in small aliquots at appropriate temperature until use.
Storage and Handling -20°C; protect from light
Sulphated Ash Ash: ≤0.5%
Typical Working Concentration For Gram Positive Bacteria & Gram Negative Bacteria : 10 mg/L
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.