Synonyms C.I. 753000; Natural Yellow 3; (E,E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)- 1,6-heptadiene-3,5-dione; Turmeric yellow; Diferuloylmethane; Diferulylmethane; Natural Yellow 3

CAS Number: 458-37-7 Molecular Formula: C21H20O6 Molecular Weight: 368.385 g/mol

Beilstein Registry Number: 2306965 EC Number: 207-280-5 MDL Number: MFCD00008365

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Product Description


Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Preparing curcuma paper

SKU 02190313-CF
Beilstein Registry Number 2306965
Biochemical Physiological Actions A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Curcumin has been cited as a potential chemopreventive agent, in addition to its chemotherapeutic activity. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.
Color Index 75300
Density 0.9348 at 59° F (NTP, 1992)
EC Number 207-280-5
Format powder
Hazard Statements H315-H319-H335
Applications Preparing curcuma paper
Melting Point 356 to 361° F (NTP, 1992)
Molecular Formula C21H20O6
Molecular Weight 368.385 g/mol
Physical Appearance Orange Powder
Product Families Description Curcumin
Product Overview Curcumin
RTECS Number MI5230000
Safety Symbol GHS07
Solubility Slightly soluble (hot) (NTP, 1992)
Storage and Handling Store at -0 °C.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.
UV Visible Absorbance λmax (ethanol): 424 - 428 nm
Vapor Pressure 3.08X10-12 mm Hg at 25 deg C (est)