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Vinblastine Sulfate

Vinblastine Sulfate

Synonyms VLB; Vincaleukoblastine sulfate salt

CAS Number: 143-67-9 Molecular Formula: C46H60N4O13S Molecular Weight: 909.061 g/mol

Beilstein Registry Number: 3659812 EC Number: 205-606-0 MDL Number: MFCD00082457

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SKU 02190287-CF
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Description

Product Description

Vinblastine Sulfate

Application Notes

Vinblastine Sulfate is used in cancer research.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Used in cancer research

Specifications
SKU 02190287-CF
Application Notes Vinblastine Sulfate is used in cancer research.
Beilstein Registry Number 3659812
Biochemical Physiological Actions Plant alkaloid that inhibits microtubule assembly by binding tubulin and inducing self-association in spiral aggregates in a reaction that appears to be regulated by the C-terminus of β-tubulin and is enhanced by GDP and GTP. Depolymerizes microtubules. Arrests the cell cycle in G2/M-phase by blocking mitotic spindle formation. Triggers Raf-1 activation, phosphorylation of bcl-2-family proteins, induction of p53 expression, and apoptosis in several tumor cell lines. Substrate of Pgp and CYP3A4.
EC Number 205-606-0
Format powder
Hazard Statements H302-H315-H318-H335
Applications Used in cancer research
Melting Point 543 to 545° F (NTP, 1992)
Molecular Formula C46H60N4O13S
Molecular Weight 909.061 g/mol
Physical Appearance White Powder
Product Families Description Vinblastine sulfate
Product Overview Vinblastine Sulfate
RTECS Number YY8400000
Safety Symbol GHS05, GHS07
Solubility greater than or equal to 10 mg/mL at 76.1° F (NTP, 1992)
Storage and Handling Store at +4 °C.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.