Dino

Retinol(All Trans)

Retinol(All Trans)

Synonyms Vitamin A alcohol; Axerophthol; Vitamin A; Vitamin A1; all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol; Anti-Infective Vitamin

CAS Number: 68-26-8 Molecular Formula: C20H30O Molecular Weight: 286.459 g/mol

Beilstein Registry Number: 403040 EC Number: 200-683-7 MDL Number: MFCD00001552

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SKU 02190268-CF
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Description

Product Description

Retinol(All Trans)

Application Notes

Retinol is an effective antioxidant displaying lipoperoxy radical scavenging activity. The interactions between Retinol and Vitamin E (α-tocopherol) in suppressing lipid peroxidation were observed in bovine retinal membrane preparations. It may influence the production of transition vesicles by stimulating the activity of a protein disulfide isomeraselike activity involved in vesicle formation. Retinol (10 µM) stimulated DNA synthesis and possibly repair mechanisms in Sertoli cells of rat.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Antioxidant||Treatment of acute promyelocytic leukemia

Specifications
SKU 02190268-CF
Application Notes Retinol is an effective antioxidant displaying lipoperoxy radical scavenging activity. The interactions between Retinol and Vitamin E (α-tocopherol) in suppressing lipid peroxidation were observed in bovine retinal membrane preparations. It may influence the production of transition vesicles by stimulating the activity of a protein disulfide isomeraselike activity involved in vesicle formation. Retinol (10 µM) stimulated DNA synthesis and possibly repair mechanisms in Sertoli cells of rat.
Beilstein Registry Number 403040
Biochemical Physiological Actions Ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR) that act as transcription factors to regulate the growth and differentiation of normal and malignant cells.
Boiling Point 279 to 280° F at 1e-06 mm Hg (NTP, 1992)
EC Number 200-683-7
Extinction Coefficient EM(325nm) = 52,480 (ethanol); E1%(324-325nm) = 1835 (ethanol)(Lit.)
Format powder
Hazard Statements H302-H315
Applications Antioxidant||Treatment of acute promyelocytic leukemia
Melting Point 144 to 147° F (NTP, 1992)
Molecular Formula C20H30O
Molecular Weight 286.459 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Gloves
Physical Appearance Orange Powder
Product Families Description Retinol
Product Overview Retinol(All Trans)
RTECS Number VH6750000
Safety Symbol GHS07
Solubility Practically insoluble (NTP, 1992)
Source Synthetic
Storage and Handling Store at -0 °C. Store Under Nitrogen. Protect from light.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.
Vapor Pressure 7.5X10-8 mm Hg at 25 deg C /Estimated/