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Ampicillin Trihydrate

Ampicillin Trihydrate

Synonyms Aminobenzylpenicillin trihydrate; alpha-Aminobenzylpenicillin trihydrate ;D[-]-α-Aminobenzylpenicillin; 6-[D(-)-α-Aminophenylacetamido]penicillanic acid

CAS Number: 7177-48-2 Molecular Formula: C16H19N3O4S·3H2O Molecular Weight: 403.45 g/mol

Beilstein Registry Number: 5399534 EC Number: 200-709-7 MDL Number: MFCD00072036

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SKU 02190147-CF
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Description

Product Description

Ampicillin Trihydrate

Application Notes

Ampicillin Trihydrate is commonly used to select for ampicillin resistance in mutated and transformed cells. It is also described for the use of inhancing luminol chemiluminescence.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Antibiotic

Specifications
SKU 02190147-CF
Application Notes Ampicillin Trihydrate is commonly used to select for ampicillin resistance in mutated and transformed cells. It is also described for the use of inhancing luminol chemiluminescence.
Beilstein Registry Number 5399534
Biochemical Physiological Actions A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli. Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
EC Number 200-709-7
Format powder
Hazard Statements H315-H317-H319-H334-H335
Applications Antibiotic
Melting Point 388 to 392° F (decomposes) (NTP, 1992)
Molecular Formula C16H19N3O4S·3H2O
Molecular Weight 403.45 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Faceshields, Gloves
Physical Appearance Powder
pKa At 25 °C ,pKa = 2.5 (-COOH),pKa = 7.3 (-NH2) (Lit.)
Product Families Description Ampicillin trihydrate
Product Overview Ampicillin Trihydrate
RTECS Number XH8425000
Safety Symbol GHS07, GHS08
Solubility 1 to 10 mg/mL at 70° F (NTP, 1992)
Sterilization of Solutions Autoclaving solutions of ampicillin will destroy activity. Solutions can be sterilized by filtration (0.22 um filter) and stored frozen (-20 °C or below). Frozen solutions can be stored for up to 3 months.
Storage and Handling Store at +4 °C.
Typical Working Concentration 100 mg/liter for both gram positive and gram negative bacteria. It is typically stable in media at 37 °C for approximately 3 days.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.