Ampicillin

Ampicillin

Synonyms D[-]-a-Aminobenzylpenicillin; 6-[D(-)-a-Aminophenylacetamido]penicillanic acid

CAS Number: 69-53-4 Molecular Formula: C16H19N3O4S Molecular Weight: 349.405 g/mol

Beilstein Registry Number: 1090925 EC Number: 200-709-7 MDL Number: MFCD00005175

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SKU 02190146-CF
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Description

Product Description

Ampicillin

Application Notes

Ampicillin is used to select bacteria cells with specific resistance during general microbiology studies. It is used to study antibiotic resistance and penetration limitations, the synergy between multiple antibiotics, certain bloodstream infections, and has been used to develop PCR assays to detect resistance genes in cerebrospinal fluid.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Antibacterial||Antibiotics

Specifications
SKU 02190146-CF
Alternate Names D[-]-a-Aminobenzylpenicillin; 6-[D(-)-a-Aminophenylacetamido]penicillanic acid
Application Notes Ampicillin is used to select bacteria cells with specific resistance during general microbiology studies. It is used to study antibiotic resistance and penetration limitations, the synergy between multiple antibiotics, certain bloodstream infections, and has been used to develop PCR assays to detect resistance genes in cerebrospinal fluid.
Beilstein Registry Number 1090925
Biochemical Physiological Actions Ampicillin is a β-lactam antibiotic with an amino group attached to the penicillin structure. Inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli. Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
EC Number 200-709-7
Format White powder
Grade Anhydrous
Hazard Statements H315-H317-H319-H334-H335
Applications Antibacterial||Antibiotics
MDL # MFCD00005175
Melting Point 388 to 392° F (decomposes) (NTP, 1992)
Molecular Formula C16H19N3O4S
Molecular Weight 349.405 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Faceshields, Gloves
Physical Appearance White Powder
pKa pKa = 2.5 (-COOH) pKa = 7.3 (-NH2) at 25 °C
Product Families Description Ampicillin
Product Overview Ampicillin
RTECS Number XH8350000
Safety Symbol GHS07, GHS08
Solubility 1 to 10 mg/mL at 70° F (NTP, 1992)
Storage and Handling Store at +4 °C.
Typical Working Concentration 100 mg/liter for both gram positive and gram negative bacteria
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.