Gentamicin Sulfate

Gentamicin Sulfate

Synonyms Garamycin; Gentamicin sulfate salt; Gentiomycin C

CAS Number: 1405-41-0 Molecular Weight: 1488.8 g/mol

EC Number: 215-778-9 MDL Number: MFCD00270181

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SKU 02190057-CF
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Description

Product Description

Gentamicin Sulfate

Application Notes

Gentamicin sulpahte is used as a selection agent (gentamicin-resistance gene) in molecular biology applications.It is used to treat many types of bacterial infections, particularly those caused by Gram-negative organisms.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Aminoglycosides||Antibacterial

Specifications
SKU 02190057-CF
Alternate Names Garamycin; Gentamicin sulfate salt; Gentiomycin C
Application Notes Gentamicin sulpahte is used as a selection agent (gentamicin-resistance gene) in molecular biology applications.It is used to treat many types of bacterial infections, particularly those caused by Gram-negative organisms.
Biochemical Physiological Actions Gentamicin causes codon misreading by binding to the 30S ribosomal subunit, blocking the translocation of peptidyl-tRNA from the acceptor site to the donor site. The bactericidal effect of gentamicin on Pseudomonas aeruginosa is exerted by the binding of gentamicin to the outer membrane, where it displaces natural cations, destabilizes the membrane, and forms holes in the cell surface. Antimicrobial spectrum: Gram-negative bacteria, Staphylococcus aureus and other Gram-positive bacteria.
EC Number 215-778-9
Grade USP Grade
Hazard Statements H317-H334
Applications Aminoglycosides||Antibacterial
Loss on Drying ≤18.0 %
MDL # MFCD00270181
Molecular Weight 1488.8 g/mol
Optical Rotation ≤1.0%
Particle Size +107° to +121°(10 mg/mL, water)
Physical Appearance White Powder
pKa 3.5 - 5.5(1 in 25, in water)
Preparation Method P261-P280-P342 + P311
Product Families Description Gentamicin sulfate
Product Overview Gentamicin Sulfate
RTECS Number LY2625000
Safety Symbol ≤1.0%
Source H2O: soluble 50 mg/mL
Storage and Handling Store at +4 °C.
Unit Definition This product is recommended for use at 50 mg/L.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.