Rolipram

Rolipram

Synonyms 4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone; ZK 62711

CAS Number: 61413-54-5 Molecular Formula: C16H21NO3 Molecular Weight: 275.348 g/mol

EC Number: 262-771-1 MDL Number: MFCD00270906

Packaging size: 100 mg

SKU 0215981080
Price:
$894.95
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Description

Product Description

Rolipram

Application Notes

Rolipram compound has been shown to inhibit PDE4 activity in human cavernosal tissue, which interrupts the signal transduction pathway of erectile response. Rolipram promotes apoptosis in HL60 cells through a cAMP-independent mechanism and has been shown to enhance neuronal survival. It is a cAMP-specific phosphodiesterase inhibitor, selective for phosphodiesterase IV.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Enzyme||Inhibitors||Substrates

Specifications
SKU 0215981080
Alternate Names 4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone; ZK 62711
Application Notes Rolipram compound has been shown to inhibit PDE4 activity in human cavernosal tissue, which interrupts the signal transduction pathway of erectile response. Rolipram promotes apoptosis in HL60 cells through a cAMP-independent mechanism and has been shown to enhance neuronal survival. It is a cAMP-specific phosphodiesterase inhibitor, selective for phosphodiesterase IV.
Biochemical Physiological Actions Selective cAMP-specific phosphodiesterase (PDE4) inhibitor.
EC Number 262-771-1
Format powder
Hazard Statements H315-H319-H335
Applications Enzyme||Inhibitors||Substrates
MDL # MFCD00270906
Molecular Formula C16H21NO3
Molecular Weight 275.348 g/mol
Pack Size 100 mg
Personal Protective Equipment Dust mask, Eyeshields, Gloves
Physical Appearance White Powder
Product Families Description Rolipram
Product Overview Rolipram
RTECS Number UY5749237
Safety Symbol GHS07
Storage and Handling Store at +4 °C.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.