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Sodium Orthovanadate

Sodium Orthovanadate

Synonyms Decavanadate; Sodium Vanadate; Sodium Vanadium Oxide

CAS Number: 13721-39-6 Molecular Formula: Na3VO4 Molecular Weight: 183.907 g/mol

EC Number: 237-287-9 MDL Number: MFCD00003511

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SKU 02159664-CF
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Description

Product Description

Sodium Orthovanadate

Application Notes

Sodium Orthovanadate is used in the diabetes study. Sodium orthovandate was used to prepare the stop solution in dephosphorylation assay of insulin receptor kinase. It was one of the reagents used in the development of Matrix ChIP that utilizes surface-immobilized antibodies.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Alkaline phosphate inhibitor

Specifications
SKU 02159664-CF
Application Notes Sodium Orthovanadate is used in the diabetes study. Sodium orthovandate was used to prepare the stop solution in dephosphorylation assay of insulin receptor kinase. It was one of the reagents used in the development of Matrix ChIP that utilizes surface-immobilized antibodies.
Biochemical Physiological Actions Inhibits ATPase, alkaline phosphatase and tyrosine phosphatase. Decavanadate, which is formed at acidic pH, inhibits inositol 1,4,5-trisphosphate (IP3)-induced Ca2+ release from endocrine cells and blocks IP3 binding to its receptor in brain tissue.Sodium orthovandate suppresses the activation of p53-mediated apoptosis triggered in response to radiation. It reduces the detrimental effects of hematopoietic syndrome, hematopoiesis and delayed genotoxic effects of induced by total body irradiation of mice. In combination with menadione, orthovandate prevents the migration of detached human glioma cells in response to anti-cancer drugs.
EC Number 237-287-9
Format powder
Hazard Statements H302 + H312 + H332
Applications Alkaline phosphate inhibitor
Molecular Formula Na3VO4
Molecular Weight 183.907 g/mol
Personal Protective Equipment Dust mask , Eyeshields, Faceshields, Gloves
Physical Appearance White Powder
Product Families Description Sodium orthovanadate
Product Overview Sodium Orthovanadate
Purity ≥96%
RTECS Number YW1120000
Safety Symbol GHS07
Storage and Handling Store at Room Temperature (15-30 °C.)
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.