Dino

Compound 48/80

Compound 48/80

CAS Number: 94724-12-6 Molecular Weight: 519.73 g/mol

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SKU 02159026-CF
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Description

Product Description

Compound 48/80

Application Notes

Compound 48/80 used to induce degranulation of GnRH-like immunoreactivity of mast cells in the brain and mesentery and for elucidating the mechanism by which anti-allergic medications suppress conjunctivitis.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Potent histamine releasing agent

Specifications
SKU 02159026-CF
Application Notes Compound 48/80 used to induce degranulation of GnRH-like immunoreactivity of mast cells in the brain and mesentery and for elucidating the mechanism by which anti-allergic medications suppress conjunctivitis.
Biochemical Physiological Actions Potent histamine releasing agent, primarily from mast cells, with a subsequent depletion of tissue histamine. It is the action of mast cell mediators on the cardiovascular system that leads to circulatory collapse. The toxicity is due to more than histamine release. It is a potent inhibitor of phospholipase C. Activates G proteins by a mechanism analogous to that of mastorparan. Inhibits calmodulin and human platelet PLC and exhibits a concentration dependent biphasic modulation of human platelet PLA2.
Format powder
Hazard Statements H301-H311-H331
Applications Potent histamine releasing agent
Molecular Weight 519.73 g/mol
Personal Protective Equipment Eyeshields, Faceshields, Gloves, respirator cartridges
Physical Appearance White Powder
Product Families Description Compound 48/80
Product Overview Compound 48/80
RTECS Number Gk2402500
Safety Symbol GHS06
Storage and Handling -20 °C. Store Desiccated
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.