Dino

Alamethicin

Alamethicin

Synonyms Antibiotic U-22324

CAS Number: 59588-86-2 Molecular Formula: C92H150N22O25 Molecular Weight: 1964.341 g/mol

Beilstein Registry Number: 5213858 MDL Number: MFCD00151517

Packaging size: 5 mg

SKU 0215900905
Price:
$212.10
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Description

Product Description

Alamethicin

Application Notes

Alamethicin applications includes increasing [32P] incorporation into phosphatidylinositol 4-phosphate and mermeabilization of sarcoplasmic reticulum vesicles.It causes fusion of lipid vesicles. It has also been used to study membrane interactions of antimicrobial peptides. It catalyzes the exchange of protons for monovalent cations with little difference in affinities and has the ability to transport cations through. It also causes hemolysis of erythrocytes and because it decreases the surface tension of water, it may have use as a detergent.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Increases [32P] incorporation into phosphatidylinositol 4-phosphate||Mermeabilization of sarcoplasmic reticulum vesicles||Fusion of lipid vesicles||Study membrane interactions of antimicrobial peptides||Catalyzes the exchange of protons||Hemolysis of erythrocytes||Detergent

Specifications
SKU 0215900905
Application Notes Alamethicin applications includes increasing [32P] incorporation into phosphatidylinositol 4-phosphate and mermeabilization of sarcoplasmic reticulum vesicles.It causes fusion of lipid vesicles. It has also been used to study membrane interactions of antimicrobial peptides. It catalyzes the exchange of protons for monovalent cations with little difference in affinities and has the ability to transport cations through. It also causes hemolysis of erythrocytes and because it decreases the surface tension of water, it may have use as a detergent.
Beilstein Registry Number 5213858
Biochemical Physiological Actions Monovalent cation ionophore; can mimic nerve action potential across artificial membranes. Increases the incorporation of 32P into phosphatidylinositol 4-phosphate and sarcoplasmic reticulum vesicles permeability. Causes fusion of lipid vesicles.
Format powder
Hazard Statements H301
Applications Increases [32P] incorporation into phosphatidylinositol 4-phosphate||Mermeabilization of sarcoplasmic reticulum vesicles||Fusion of lipid vesicles||Study membrane interactions of antimicrobial peptides||Catalyzes the exchange of protons||Hemolysis of erythrocytes||Detergent
Molecular Formula C92H150N22O25
Molecular Weight 1964.341 g/mol
Pack Size 5 mg
Personal Protective Equipment Eyeshields, Faceshields, Gloves, respirator cartridges
Physical Appearance Tan Powder
Product Families Description Alamethicin
Product Overview Alamethicin
Purity ≥50%
RTECS Number AY1900000
Safety Symbol GHS06
Source Trichoderma viride
Storage and Handling Store at -20 °C.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.