Thapsigargin

Thapsigargin

CAS Number: 67526-95-8 Molecular Weight: 650.762 g/mol

MDL Number: MFCD00083511

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SKU 02158999-CF
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Description

Product Description

Thapsigargin

Application Notes

Thapsigargin may be used to distinguish between discrete intracellular Ca2+ pools. It induces apoptosis in rat thymocytes and in human hepatoma cells.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Apoptosis inducer||Calcium releaser

Specifications
SKU 02158999-CF
Application Notes Thapsigargin may be used to distinguish between discrete intracellular Ca2+ pools. It induces apoptosis in rat thymocytes and in human hepatoma cells.
Biochemical Physiological Actions Potent, cell-permeable, IP3-independent intracellular calcium releaser. Blocks the transient increase in intracellular Ca2+ induced by angiostatin and endostatin. Induces apoptosis by disrupting intracellular free Ca2+ levels; incorporated into chemotherapeutic prodrug formulations.
Format Crystalline powder
Hazard Statements H315-H319-H334-H335
Applications Apoptosis inducer||Calcium releaser
MDL # MFCD00083511
Molecular Weight 650.762 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Faceshields, Gloves
Physical Appearance White Crystalline Powder
Product Families Description Thapsigargin
Product Overview Thapsigargin
Purity ≥97%
Refractive Index n20D 1.54 (Predicted)(Lit.)
Safety Symbol GHS07, GHS08
Source Thapsia garganica
Storage and Handling Store at -20 °C.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.