Conduritol B Epoxide

Conduritol B Epoxide

Synonyms DL -1,2-Anhydro-myo-inositol; CBE

CAS Number: 6090-95-5 Molecular Formula: C6H10O5 Molecular Weight: 162.141 g/mol

MDL Number: MFCD00077326

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SKU 02158893-CF
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Description

Product Description

Conduritol B Epoxide

Application Notes

In vitro exposure of cells to CBE has been reported to lead to up-regulation of CD1d (cluster of differentiation 1d) expression by THP-1 cells, which is related to an increase in mRNA expression. Has been employed in in vitro and animal models for Gaucher's disease. Treatment of murine peritoneal macrophages with this inhibitor does not seem to affect lysozyme enzyme release to the medium, cell viability, or levels of intracellular lysosomal enzymes, other than & beta-glucosidase activity.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Enzymes||Inhibitors||Substrates

Specifications
SKU 02158893-CF
Alternate Names DL -1,2-Anhydro-myo-inositol; CBE
Application Notes In vitro exposure of cells to CBE has been reported to lead to up-regulation of CD1d (cluster of differentiation 1d) expression by THP-1 cells, which is related to an increase in mRNA expression. Has been employed in in vitro and animal models for Gaucher's disease. Treatment of murine peritoneal macrophages with this inhibitor does not seem to affect lysozyme enzyme release to the medium, cell viability, or levels of intracellular lysosomal enzymes, other than & beta-glucosidase activity.
Biochemical Physiological Actions β-Glucosidase inhibitor.
Format powder
Applications Enzymes||Inhibitors||Substrates
MDL # MFCD00077326
Molecular Formula C6H10O5
Molecular Weight 162.141 g/mol
Personal Protective Equipment Eyeshields, Gloves, Respirator filter
Physical Appearance White Powder
Product Families Description Conduritol B Epoxide
Product Overview Conduritol B Epoxide
Purity ≥97%
Refractive Index n20D 1.73(Lit.)
Storage and Handling -20 °C; Desiccate
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.