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1,1-Dimethylbiguanide Hydrochloride

1,1-Dimethylbiguanide Hydrochloride

Synonyms N,N-Dimethylimidodicarbonimidic diamine; 1,1-Dimethylbiguanide hydrochloride; DMGG; LA-6023; Metformin hydrochloride

CAS Number: 1115-70-4 Molecular Formula: C4H12ClN5 Molecular Weight: 165.625 g/mol

EC Number: 214-230-6 MDL Number: MFCD00012582

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SKU 02157805-CF
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$350.00
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Description

Product Description

1,1-Dimethylbiguanide Hydrochloride

Application Notes

1,1-Dimethylbiguanide Hydrochloride has various medical uses such as in polycystic ovary syndrome, non-alcoholic fatty liver disease and diabetes mellitus type 2. It may also reduce weight gain in people taking atypical antipsychotics. 1,1-Dimethylbiguanide hydrochloride is suitable biguanide agent used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

An antidiabetic agent

Specifications
SKU 02157805-CF
Application Notes 1,1-Dimethylbiguanide Hydrochloride has various medical uses such as in polycystic ovary syndrome, non-alcoholic fatty liver disease and diabetes mellitus type 2. It may also reduce weight gain in people taking atypical antipsychotics. 1,1-Dimethylbiguanide hydrochloride is suitable biguanide agent used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels.
Biochemical Physiological Actions 1,1-Dimethylbiguanide hydrochloride (Metformin) is an antidiabetic agent that reduces blood glucose levels and improves insulin sensitivity. Its metabolic effects, including the inhibition of hepatic gluconeogenesis, are mediated at least in part by activation of the LKB1-AMPK (AMP-activated protein kinase) pathway. Activation of this pathway also appears to be involved in the antiproliferative and proapoptotic actions of metformin in cancer cell lines.
EC Number 214-230-6
Format powder
Hazard Statements H302-H315-H319
Applications An antidiabetic agent
Molecular Formula C4H12ClN5
Molecular Weight 165.625 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Gloves
Physical Appearance White Powder
Product Families Description 1,1-Dimethylbiguanide
Product Overview 1,1-Dimethylbiguanide Hydrochloride
RTECS Number DU1800000
Safety Symbol GHS07
Solubility In <a class="pubchem-internal-link CID-962" href="https://pubchem.ncbi.nlm.nih.gov/compound/water">water</a>, 1.06X10+6 mg/L (miscible) at 25 deg C (est)
Storage and Handling Store at Room Temperature (15-30 °C).
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Vapor Pressure 7.58X10-5 mm Hg at 25 deg C (est)