Hygromycin B Solution

Hygromycin B Solution

Synonyms Antihelmycin; Hygromix-8

CAS Number: 31282-04-9 Molecular Formula: C20H37N3O13

Beilstein Registry Number: 6755837 EC Number: 250-545-5 MDL Number: MFCD06795479

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SKU 02157513-CF
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Description

Product Description

Hygromycin B Solution

Application Notes

Hygromycin has been used to select drug-resistant stable transfectants after transfer of the hygromycin phosphotransferase gene in a variety of cell culture applications. It is used in gene transfer experiments as a selection agent.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Antibacterial and antifungal agent

Specifications
SKU 02157513-CF
Alternate Names Antihelmycin; Hygromix-8
Application Notes Hygromycin has been used to select drug-resistant stable transfectants after transfer of the hygromycin phosphotransferase gene in a variety of cell culture applications. It is used in gene transfer experiments as a selection agent.
Beilstein Registry Number 6755837
Biochemical Physiological Actions Antibacterial and antifungal. Mode of action: Inhibition of protein synthesis, it interfere with translocation of the 70S ribosome, by inducing the misreading of the m-RNA template in prokaryotes and eukaryotes. It selectively penetrates cells that have been rendered permeable by virus infection.
EC Number 250-545-5
Format liquid
Formulation Hygromycin B is provided as a caramel-colored solution in water. Not prepared under sterile conditions. If a sterile solution is desired; working solutions of Hygromycin B in aqueous media can be passed through a 0.2 micron filter before use. Do not autoclave solutions of Hygromycin B.
Hazard Statements H301 + H311-H318-H330-H334
Applications Antibacterial and antifungal agent
MDL # MFCD06795479
Molecular Formula C20H37N3O13
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator, Gloves, multi-purpose combination respirator cartridge, respirator filter
Physical Appearance Clear Golden Yellow Liquid
pKa 7.1 and 8.8(Lit.)
Product Families Description Hygromycin B
Product Overview Hygromycin B Solution
Purity ≥80%
RTECS Number WK2130000
Safety Symbol GHS05, GHS06, GHS08
Specific Activity ~450,000 u/mL
Sterilization of Solutions Solutions should be sterilized by means of a 0.2 micron filter. Do not autoclave solutions.
Storage and Handling Store at +4 °C.
Typical Working Concentration For use as a selective agent, the suggested concentration range is 100- 800 μg/mL
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.