Tobramycin

Tobramycin

Synonyms O-[3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)]-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribohexopyranosyl-(1→4)]-2-deoxy-D-streptamine; Deoxykanamycin B ; Gotabiotic ; Nebramycin

CAS Number: 32986-56-4 Molecular Formula: C18H37N5O9 Molecular Weight: 467.52 g/mol

Beilstein Registry Number: 1357507 EC Number: 251-322-5 MDL Number: MFCD00077885

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SKU 02156926-CF
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Description

Product Description

Tobramycin

Application Notes

Tobramycin is an aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius. It is effective against gram-negative bacteria, especially the pseudomonas species. It is not effective against Enterococci. It is used to inhibit bacterial protein synthesis. It is used to treat pseudomonas aeruginosa lung infections and is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, sepsis, respiratory infections, osteomyelitis, and other soft-tissue infections. It is a potential therapy for sinus infections.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Antibacerial||Antibiotics

Specifications
SKU 02156926-CF
Alternate Names O-[3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)]-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribohexopyranosyl-(1→4)]-2-deoxy-D-streptamine; Deoxykanamycin B ; Gotabiotic ; Nebramycin
Application Notes Tobramycin is an aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius. It is effective against gram-negative bacteria, especially the pseudomonas species. It is not effective against Enterococci. It is used to inhibit bacterial protein synthesis. It is used to treat pseudomonas aeruginosa lung infections and is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, sepsis, respiratory infections, osteomyelitis, and other soft-tissue infections. It is a potential therapy for sinus infections.
Beilstein Registry Number 1357507
Biochemical Physiological Actions Tobramycin is an aminoglycoside.Its Mode of Action is: it binds to 70S ribosomal subunit; inhibits translocation;and hence elicits miscoding. Spectrum of Activity: Gram negative bacteria.
EC Number 251-322-5
Applications Antibacerial||Antibiotics
MDL # MFCD00077885
Molecular Formula C18H37N5O9
Molecular Weight 467.52 g/mol
pH Basic substance
Physical Appearance White Powder
Product Families Description Tobramycin
Product Overview Tobramycin
RTECS Number WK2100000
Solubility Water Solubility1000 mg/ml
Storage and Handling Store at +4 °C.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Vapor Pressure 2.37X10-21 mm Hg at 25 deg C (est)