Thiamphenicol

Thiamphenicol

Synonyms D -threo-2,2-dichloro-N-[ β-hydroxy-α-(hydroxymethyl)-p-(methyl- sulfonyl)phenethyl]-acetamide

CAS Number: 15318-45-3 Molecular Formula: C12H15Cl2NO5S Molecular Weight: 356.214 g/mol

Beilstein Registry Number: 2819542 EC Number: 239-355-3 MDL Number: MFCD00467983

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SKU 02156846-CF
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Description

Product Description

Thiamphenicol

Application Notes

Thiamphenicol is an antibiotic that has been used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Antibacterial||Antibiotics

Specifications
SKU 02156846-CF
Alternate Names D -threo-2,2-dichloro-N-[ β-hydroxy-α-(hydroxymethyl)-p-(methyl- sulfonyl)phenethyl]-acetamide
Application Notes Thiamphenicol is an antibiotic that has been used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.
Beilstein Registry Number 2819542
Biochemical Physiological Actions Thiamphenicol inhibits mitochondrial protein synthesis of proteins such as cytochrome c oxidase.
EC Number 239-355-3
Applications Antibacterial||Antibiotics
MDL # MFCD00467983
Molecular Formula C12H15Cl2NO5S
Molecular Weight 356.214 g/mol
Personal Protective Equipment Eyeshields, Gloves, respirator filter
Physical Appearance White; Free Flowing Powder
Product Families Description Thiamphenicol
Product Overview Thiamphenicol
RTECS Number AB6680000
Solubility >53.4 [ug/mL]
Storage and Handling Store at Room Temperature (15-30 °C).
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.