Sorbitol Dehydrogenase

Sorbitol Dehydrogenase

Synonyms L-Iditol dehydrogenase; Polyol dehydrogenase; L-Iditol: NAD+ 5-oxidoreductase; EC 1.1.1.14; SDH

CAS Number: 9028-21-1

MDL Number: MFCD00131994

Packaging size: 5 mg

SKU 0215664205
Price:
$487.35
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Description

Product Description

Sorbitol Dehydrogenase

Application Notes

Sorbitol dehydrogenase has been used in a study to investigate osmotic stress induced oxidative damage as a possible mechanism of cataract formation in diabetes.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Cabrohydrate metabolism

Specifications
SKU 0215664205
Alternate Names L-Iditol dehydrogenase; Polyol dehydrogenase; L-Iditol: NAD+ 5-oxidoreductase; EC 1.1.1.14; SDH
Application Notes Sorbitol dehydrogenase has been used in a study to investigate osmotic stress induced oxidative damage as a possible mechanism of cataract formation in diabetes.
Biochemical Physiological Actions Activity of sorbitol dehydrogenase increases in diabetic animals.
Format powder
Hazard Statements H317
Applications Cabrohydrate metabolism
MDL # MFCD00131994
Pack Size 5 mg
Personal Protective Equipment Eyeshields, Gloves, respirator filter
Physical Appearance Powder
Product Families Description Sorbitol Dehydrogenase
Product Overview Sorbitol Dehydrogenase
Source Sheep Liver
Specific Activity ≥20 u/mg protein
Specificity Reduces L-iditol to L-sorbose. Also acts on D-glucitol and other closely related sugar alcohols. Allows the reduction of ketones to polyols. The reduction of D-fructose is favored. However; alkaline pH shifts the equilibrium in favor of sorbitol oxidation. SDH does not oxidize erythritol; D- or L-arabitol; D-iditol; D-mannitol or inositol. It will not reduce D-tagatose; D-mannoheptulose; D-glucose; DL-glyceraldehyde; pyruvate; 2-oxolutarate or acetaldehyde.
Storage and Handling Store at -0 °C.
Unit Definition One unit will convert 1.0 umole of D-fructose to D-sorbitol per minute at pH 7.6 at 25 °C.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.