Pimaricin

Pimaricin

Synonyms Antibiotic A-5283; Mycophyt; Natacyn; Pimafucin; Tennecetin; Natamycin preparation

CAS Number: 7681-93-8 Molecular Formula: C33H47NO13 Molecular Weight: 665.733 g/mol

Beilstein Registry Number: 1614878 EC Number: 231-683-5 MDL Number: MFCD00135085

Packaging size: 20 mL

SKU 0215625420
Price:
$297.45
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Description

Product Description

Pimaricin

Application Notes

Pimaricin is an amphoteric macrolide antifungal antibiotic from Streptomyces natalensis or S. chattanoogensis. It is used for a variety of fungal infections, mainly topically. It is used as an ergosterol and cholesterol binding agent to study lipid bilayer dynamics, especially in fungal cells. It is used to study pimaricin biosynthesis1 and as a fungicide in agar media.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Antibiotic

Specifications
SKU 0215625420
Alternate Names Antibiotic A-5283; Mycophyt; Natacyn; Pimafucin; Tennecetin; Natamycin preparation
Application Notes Pimaricin is an amphoteric macrolide antifungal antibiotic from Streptomyces natalensis or S. chattanoogensis. It is used for a variety of fungal infections, mainly topically. It is used as an ergosterol and cholesterol binding agent to study lipid bilayer dynamics, especially in fungal cells. It is used to study pimaricin biosynthesis1 and as a fungicide in agar media.
Beilstein Registry Number 1614878
Biochemical Physiological Actions An antifungal polyene macrolide that binds specifically to ergosterol and blocks fungal growth. However, unlike nysatin and filipin, pimaricin does not change the permeability of the plasma membrane.
EC Number 231-683-5
Format Suspension
Applications Antibiotic
MDL # MFCD00135085
Melting Point 290 dec °C
Molecular Formula C33H47NO13
Molecular Weight 665.733 g/mol
Pack Size 20 mL
Personal Protective Equipment Eyeshields, Gloves
pH 5,5-7,5 (1 % w/v solution in previously neutralised mixture of 20 parts <a class="pubchem-internal-link CID-6228" href="https://pubchem.ncbi.nlm.nih.gov/compound/dimethylformamide">dimethylformamide</a> and 80 parts of <a class="pubchem-internal-link CID-962" href="https://pubchem.ncbi.nlm.nih.gov/compound/water">water</a>)
Physical Appearance Milky Suspension
Product Families Description Pimaricin
Product Overview Pimaricin
RTECS Number TK3325000
Solubility <h5 class="minor-section-title">Water Solubility</h5>4100 mg/L (at 21 °C)
Storage and Handling Store at + 4 °C. Protect from light.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.